Publications by authors named "Alaulddin Hazim Mohammed"
Article Synopsis
- Traditional cancer treatments face issues like toxicity, resistance, and high costs, prompting interest in bioactive phytochemicals that target multiple molecular pathways with less harm.
- A network pharmacology approach was employed to analyze the active constituents for liver cancer treatment, utilizing databases for target retrieval and gene expression analysis.
- Key survival-related genes (HSP90AA1, ESR1, CYP3A4, CDK1, MMP9) were identified, with four potent phytochemicals potentially influencing HSP90AA1 as a therapeutic target, supported by molecular dynamics simulation results showing stable interactions.
