Publications by authors named "Alan V Kalueff"
Article Synopsis
- The modern lifestyle leads to increased emotional stress, contributing to anxiety disorders and highlighting the need for safe treatment alternatives due to the side effects of current pharmaceuticals.
- A study using BALB/c mice demonstrated that ultrasound exposure can model anxiety-like behaviors and impact certain neurobiological markers, including AMPA receptor expression and inflammation.
- The administration of herbal antioxidant/anti-inflammatory treatments (HAT) not only prevented anxiety-like behaviors but also normalized biochemical imbalances associated with stress, suggesting that natural remedies may offer effective management for stress-related emotional issues.
With an estimated 207,090 patients diagnosed with breast cancer in 2010, the role of chemotherapy-induced cognitive impairment is of growing importance. Studies to determine the impact of chemotherapy-induced cognitive impairment have been hindered by difficulties in study-design, in particular, study methodology. Here, we present a review of existing studies and discuss several mechanisms for chemotherapy-induced neurocognitive impairment in breast cancer patients, such as direct neurotoxic injury, telomere shortening, oxidative stress, cytokine dysregulation, estrogen-mediated effects, and the role of certain genetic polymorphisms.
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