State of the art in trueness and interlaboratory harmonization for 10 analytes in general clinical chemistry.

Context: Harmonization and standardization of results among different clinical laboratories is necessary for clinical practice guidelines to be established.

Objective: To evaluate the state of the art in measuring 10 routine chemistry analytes.

Design: A specimen prepared as off-the-clot pooled sera and 4 conventionally prepared specimens were sent to participants in the College of American Pathologists Chemistry Survey.