Publications by authors named "Alan P Rotchford"
Prcis: Intraocular pressure (IOP) decreased with age in a population-based study in Nepal, from a mean of 14.1 mm Hg among those 60-64 years old to 13.0 mm Hg among those 80 years old or older.
View Article and Find Full Text PDFAims: To report the number and demographic distribution of patients receiving intraocular pressure (IOP)-lowering medications across the whole population of Scotland for the years 2010-2017 and, using national census data, show how the observed changes compare with those predicted by the increasing age of the population structure over this period.
Methods: Data were sourced from the Prescribing Information System of the NHS Information and Statistics Division for Scotland. The number of patients dispensed any IOP-lowering medication from a community pharmacy during each calendar year was collected by gender and by 5-year age bands.
Background/aims: To report refractive outcomes from an National Health Service (NHS) cataract surgery service and assess if results meet suggested benchmark standard.
Methods: Details of all patients undergoing cataract surgery in the Southern General and New Victoria hospitals in Glasgow, UK, between November 2006 and December 2016 were prospectively entered into an electronic database. Patients were reviewed 4 weeks postoperatively in the eye clinic and underwent refraction at their local optometrist prior to this appointment.
Aim: To assess medium-term to long-term outcomes of a cohort of repeat trabeculectomy augmented with mitomycin C (MMC).
Methods: A prospective evaluation of consecutive separate site repeat MMC-augmented trabeculectomies undertaken at a single institution between October 2000 and December 2012. Information regarding visual acuity (VA), intraocular pressure (IOP), visual field progression, postoperative interventions, surgery complications and success of surgery are presented.
Importance: Establishing the true therapeutic effect of eyedrops when initiating glaucoma therapy is important. Accurate prediction of the intraocular pressure (IOP)-lowering response in the fellow eye when using a monocular trial eliminates the need for additional office visits to confirm the therapeutic effect.
Objective: To investigate the validity of the monocular trial in patients commencing topical glaucoma treatment at different time points.
Purpose: To describe the pattern of glaucoma-service delivery in Scotland and identify areas for improvement, taking into account Scottish General Ophthalmic Services (GOS) arrangements and the Eye Care Integration project, and to design Scottish Intercollegiate Guidelines Network (SIGN) guidelines to refine the primary and secondary interface of glaucoma care.
Materials And Methods: A glaucoma-survey questionnaire was sent to all consultant glaucomatologists in Scotland. The design of SIGN guidelines was based on the results of the questionnaire using SIGN methodology.
Repeatability of measurements of effectiveness of glaucoma medication.
Br J Ophthalmol
December 2012
Aims: To determine short-term repeatability of the effect of intraocular pressure (IOP) reducing medication and the number of repeated measurements necessary to estimate therapeutic effect with a given degree of precision.
Methods: IOP was measured at 8:00, 11:00 and 16:00 h at each of three weekly visits in untreated patients with primary open-angle glaucoma or ocular hypertension. After starting travaprost (0.
Aims: To investigate the day-to-day repeatability of intraocular pressure (IOP) measurements.
Methods: A prospective cohort study of untreated patients presenting with primary open-angle glaucoma or ocular hypertension presenting with IOP>21 mm Hg. IOP was measured by masked Goldmann tonometry at 08:00, 11:00 and 16:00 at each of the three weekly visits.
Background: To determine the success of repeat trabeculectomy augmented with mitomycin C in a cohort of patients who had undergone previously failed trabeculectomy surgery.
Design: A consecutive cohort series of patients.
Participants: Fifty patients undergoing augmented trabeculectomy surgery following a previously failed trabeculectomy and at least 12 months' follow up.
Objective: To investigate the validity of the monocular therapeutic trial of therapy in patients commencing topical glaucoma treatment.
Design: Prospective intention-to-treat cohort study of untreated patients presenting with open-angle glaucoma or ocular hypertension.
Participants: We included 30 treatment-naïve subjects.
The management of patients presenting with advanced glaucoma presents a challenge to glaucoma clinicians. Presentation with advanced visual field loss is an important risk factor for progression to blindness in the affected eye(s) during the patients' lifetime. Maximising intraocular pressure (IOP) control in such situations is likely to minimise the risk of further visual field deterioration thus either preventing or slowing progression to blindness.
View Article and Find Full Text PDFAims: To determine the value of daytime and 24-h phasing in patients treated for progressive glaucoma despite apparently adequate intraocular pressure (IOP) control.
Methods: A retrospective analysis of a cohort of patients that had undergone either daytime phasing (08:00-18:00) or 24-h phasing was conducted. IOP measurements were compared between those taken in clinic, daytime phasing and 24-h phasing.
Purpose: To determine (1) the extent to which the definition of success of glaucoma surgery varies in the literature and (2) the degree to which the reported outcome after trabeculectomy is affected by the criteria used to define success.
Design: A systematic review of the literature and application of definitions to a retrospective cohort.
Participants: A cohort of 100 patients who previously underwent trabeculectomy.
Purpose: To describe a modified technique for combined cataract and glaucoma drainage surgery involving a small flap (micro) trabeculectomy combined with phaco-emulsification (PMT). To assess the level of intraocular pressure (IOP) control achieved by this procedure in comparison with microtrabeculectomy (MT) alone.
Methods: In this retrospective controlled case series records were reviewed for 37 consecutive low-risk patients undergoing PMT augmented with 5-fluorouracil (5-FU) and 37 low-risk subjects undergoing MT with 5-FU.
Purpose: To assess the long-term success rate and to determine factors that predict survival after 5-fluorouracil-augmented needling revision of poorly functioning trabeculectomy blebs.
Design: Prospective observational cohort study.
Participants: Eighty-one consecutive patients undergoing bleb needling.
Purpose: To assess the effect of cataract surgery on trabeculectomy blebs that have previously had successful needling revision.
Study Design: A retrospective controlled study.
Patients And Methods: A cohort of patients undergoing needling of a poorly functioning trabeculectomy bleb was collected.
Glaucoma drainage surgery in diabetic patients is associated with a relatively poor prognosis due to increased scarring at the site of surgery, secondary to increased proliferation of human Tenon's capsule fibroblasts (hTCF). This is in marked contrast to diabetic wound healing at other sites, where it is generally impaired. The aim of this study was to determine why diabetics show an increased ocular scarring response in comparison to that found at other sites.
View Article and Find Full Text PDFBackground: Data on exfoliation syndrome (XFS) in Africans are scarce.
Objective: To determine the prevalence and clinical features of XFS among black South Africans.
Design: Random cross-sectional samples of the black population aged 40 years or older from 2 districts in South Africa: Hlabisa, in northern KwaZulu-Natal Province, and Temba, North West Province.
Objective: To determine the prevalence and features of glaucoma in an urban South African black population.
Design: Random sampling cross-sectional population survey.
Participants: Black residents of Temba, North West Province, South Africa, age > or =40 years.