Publications by authors named "Alan Mejstrik"
Background: Individualised bedside adjustment of mechanical ventilation is a standard strategy in acute coma neurocritical care patients. This involves customising positive end-expiratory pressure (PEEP), which could improve ventilation homogeneity and arterial oxygenation. This study aimed to determine whether PEEP titrated by electrical impedance tomography (EIT) results in different lung ventilation homogeneity when compared to standard PEEP of 5 cmHO in mechanically ventilated patients with healthy lungs.
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- Out-of-hospital cardiac arrest (OHCA) has a low survival rate, and the effectiveness of an early invasive treatment approach compared to standard care is unclear.
- A randomized clinical trial in Prague involved 256 adults with OHCA to assess whether an invasive strategy improves neurologically favorable survival at 180 days.
- The trial was halted early for futility, showing that 31.5% of the invasive group had a good neurologic outcome compared to 22.0% in the standard care group.