Publications by authors named "Alan M Golichowski"
Placenta percreta is a problem encountered with increasing frequency due to the rising rate of cesarean delivery. Conservative management of this condition is associated with decreased perioperative morbidity. When hysterectomy is necessary, a laparoscopic approach can provide additional benefits.
View Article and Find Full Text PDFObjective: The objective of the study was to determine whether vaginal preparation with povidone iodine before cesarean delivery decreased the risk of postoperative maternal morbidities.
Study Design: The design of the study was a randomized, controlled trial in women undergoing cesarean delivery with subjects assigned to have a preoperative vaginal cleansing with povidone iodine or to a standard care group (no vaginal wash). The primary outcome was a composite of postoperative fever, endometritis, sepsis, readmission, wound infection, or complication.
Article Synopsis
- * In a case of a pregnant woman with sporadic Creutzfeldt-Jakob disease (CJD), researchers found that while the brain contained abnormal prion proteins, the uterus, placenta, and amniotic fluid showed only normal PrP proteins that were susceptible to digestion.
- * Ongoing research aims to determine if there is any prion infectivity present in the amniotic fluid through advanced bioassays, as initial findings did not show abnormal prion proteins in the reproductive tissues.
Objective: To determine the optimal first-line tocolytic agent for treatment of premature labor.
Methods: We performed a quantitative analysis of randomized controlled trials of tocolysis, extracting data on maternal and neonatal outcomes, and pooling rates for each outcome across trials by treatment. Outcomes were delay of delivery for 48 hours, 7 days, and until 37 weeks; adverse effects causing discontinuation of therapy; absence of respiratory distress syndrome; and neonatal survival.