Publications by authors named "Alan G Johnson"
This paper reviews the progress made in understanding the mechanical behaviour of the biliary system. Gallstones and diseases of the biliary tract affect more than 10% of the adult population. The complications of gallstones, i.
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- The study evaluated the effectiveness of a specialized upper-gastrointestinal haemorrhage (UGIH) unit by using the Rockall scoring system to categorize patient risk factors for mortality.
- A total of 900 patients were analyzed, revealing that the mortality rate at the specialized unit (8.1%) was lower than the national average (14%), despite treating a higher risk population.
- The findings suggest that the specialized UGIH unit significantly improves patient outcomes, indicating that there are still opportunities for further reduction in mortality rates in UGIH cases.
Background And Aim: Medically refractory upper gastrointestinal hemorrhage (UGIH) is a complex clinical problem. Selection of patients suitable for surgery is difficult and often involves subjective clinical judgment. The simplified acute physiology score (SAPS) II is a validated predictor of mortality in the intensive care setting.
View Article and Find Full Text PDFObjective: The metaplastic change of Barrett's oesophagus is linked to both acid and duodenal reflux together with impaired motility. Proton pump inhibitors (PPI) reduce acid reflux, but no treatment is available that reduces duodenogastro-oesophageal reflux (DGOR). The aim of this study was to investigate whether adding a prokinetic to PPI treatment could improve oesophageal motility and subsequently reduce reflux.
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