Publications by authors named "Alan Chakrin"

Article Synopsis
  • The study focused on burn patients with intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS), examining the levels of antithrombin (AT) and cytokines in their plasma and peritoneal fluid (PF).
  • Results showed significantly elevated cytokine levels in the plasma and PF of burn patients compared to normal plasma, while AT levels were lower in these patients.
  • Findings suggest that peritoneal fluid acts as a reservoir for cytokines during resuscitation and may disrupt homeostasis in severely burned patients, especially those who did not survive.
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Due to a successful Haemophilus Influenzae (HIF) vaccination program, this pathogen is no longer a major contributor to childhood morbidity and mortality. The effect on adult acquisition of HIF is unknown. The purpose of this study was to determine HIF infection frequency in severely burned patients.

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Abdominal Compartment Syndrome (ACS) has multiple causes, and decompressive laparotomy has been the most frequent modality to prevent worsening cardiovascular, respiratory, and renal function. This pilot study evaluated the utility of percutaneous drainage (PD) of peritoneal fluid compared with decompressive laparotomy in burn patients. A 26-month review was conducted.

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