Publications by authors named "Alan Cesar Nunes De Moraes"
Article Synopsis
- Radiation-induced liver disease (RILD) is a significant issue stemming from radiotherapy, prompting research into using granulocyte colony-stimulating factor (G-CSF) as a potential treatment to improve liver function.
- Researchers conducted experiments on C57BL/6 mice that underwent alcohol-induced liver injury, administering G-CSF before or after irradiation to evaluate its effects.
- G-CSF given before radiation showed promising results, improving liver health and survival rates, while post-irradiation treatment had limited benefits, indicating that G-CSF might be more effective if administered prior to radiation exposure.
Article Synopsis
- Resveratrol, a compound found in red grapes and peanuts, shows potential in reducing liver damage, but its long-term effectiveness needed investigation.
- In a study using mice with acetaminophen-induced liver injury, researchers administered resveratrol for 60 days after the initial damage, observing positive changes in liver structure and function.
- Results indicated that long-term resveratrol treatment significantly improved liver recovery, as noted by restored cellular features and a normalization of various biochemical markers.
Purpose: This study aimed to investigate radiation-induced lesions on the skin in an experimental animal model. Cutaneous wounds were induced in Wistar rats by 4 MeV energy electron beam irradiation, using a dose rate of 240 cGy/min, for 3 different doses (10 Gy, 40 Gy, and 60 Gy). The skin was observed 5, 10, and 25 days (D) after ionizing radiation exposition.
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