A longitudinal examination of perinatal testosterone, estradiol and vitamin D as predictors of handedness outcomes in childhood and adolescence.

The developmental origins of handedness remain elusive, though very early emergence suggests individual differences manifesting could play an important role. Prenatal testosterone and Vitamin D exposure are considered, yet findings and interpretations remain equivocal. We examined n = 767 offspring from a population-based pregnancy cohort (The Raine Study) for whom early biological data and childhood/adolescent handedness data were available.

Judgements of attractiveness of the opposite sex and nostril differences in self-rated mood: The effects of androstenol.

Androstenol has been reported to influence judgements of attractiveness and to affect participants' mood. In the present study, participants were asked to sniff androstenol or a control odour (pure ethanol) unilaterally with the left or right nostril. Subsequently, they rated the attractiveness of photographs of the opposite sex and their own feelings on four mood scales.

Where next for laterality research? Looking back and looking forward.

While paying attention to the recommendations of Ocklenburg, Berretz, Packheiser, and Friedrich (2020) in the target article, researchers in the field of laterality should attempt to: (1) solve the long-standing puzzle of the relationship between handedness and language lateralization; (2) further explore the genetic bases of manual and cerebral asymmetry and of their associations with psychiatric and neurodevelopmental conditions; (3) explore the adaptive significance of laterality for humans and non-humans and elucidate the relationships of asymmetry across species; and (4) embrace developing technologies to investigate the interaction between the hemispheres during the performance of everyday tasks.

Digit ratio (2D:4D) and handedness: A meta-analysis of the available literature.

The Geschwind-Behan-Galaburda and sexual differentiation models predict an association between elevated foetal androgen exposure and left-handedness whereas the callosal hypothesis predicts the opposite. We present a meta-analysis of correlations between handedness and digit ratio (2D:4D), a putative marker of prenatal testosterone. Left-handedness predicted low (male-typical) right-hand digit ratio (R2D:4D), high (female-typical) left-hand digit ratio (L2D:4D), and low R2D:4D-L2D:4D directional asymmetry (D).

An examination of the influence of prenatal sex hormones on handedness: Literature review and amniotic fluid data.

Competing theories have posited roles for foetal androgen exposure in the development of human handedness. However, due to practical and ethical considerations, few studies have used hormonal measures to examine this possibility. The current paper reviews this literature and reveals a generally inconsistent pattern of results.

Fractionating negative and positive affectivity in handedness: Insights from the Reinforcement Sensitivity Theory of personality.

The Annett Hand Preference Questionnaire (AHPQ), as modified by Briggs and Nebes [(1975). Patterns of hand preference in a student population. Cortex, 11(3), 230-238.

Handedness and behavioural inhibition system/behavioural activation system (BIS/BAS) scores: A replication and extension of Wright, Hardie, and Wilson (2009).

The Annett Hand Preference Questionnaire (AHPQ) as modified by Briggs and Nebes was administered along with Carver and White's behavioural inhibition system (BIS) and behavioural activation system (BAS) scale and a shortened form of the Big Five personality questionnaire to 92 university students. After eliminating the data from five respondents who reported having changed handedness and one outlier, there was a significant sex difference in mean BIS scores, with females (n = 43) scoring higher than males (n = 43). Replicating the results of Wright, Hardie and Wilson, non-right-handers (n = 36) had significantly higher mean BIS score than right-handers (n = 50).

The enigmatic linguistic cerebellum: clinical relevance and unanswered questions on nonmotor speech and language deficits in cerebellar disorders.

Clinical case descriptions and experimental evidence dating back to the early part of the 19th century from time to time documented a range of nonmotor cognitive and affective impairments following cerebellar pathology. However, a causal relationship between disruption of nonmotor cognitive and affective skills and cerebellar disease was dismissed for several decades and the classical view of the cerebellum as a mere coordinator of autonomic and somatic sensorimotor function prevailed for more than two centuries in behavioural neuroscience. The ignorance of early clinical evidence suggesting a much richer and complex role for the cerebellum than a pure sensorimotor one is remarkable given that in addition: 1) the cerebellum contains more neurons than the rest of the combined cerebral cortex and 2) no other structure has as many connections with other parts of the brain as the cerebellum.

Consensus paper: Language and the cerebellum: an ongoing enigma.

In less than three decades, the concept "cerebellar neurocognition" has evolved from a mere afterthought to an entirely new and multifaceted area of neuroscientific research. A close interplay between three main strands of contemporary neuroscience induced a substantial modification of the traditional view of the cerebellum as a mere coordinator of autonomic and somatic motor functions. Indeed, the wealth of current evidence derived from detailed neuroanatomical investigations, functional neuroimaging studies with healthy subjects and patients and in-depth neuropsychological assessment of patients with cerebellar disorders shows that the cerebellum has a cardinal role to play in affective regulation, cognitive processing, and linguistic function.

Reduced dream-recall frequency in left-handed adolescents: a replication.

The ability to recall a dream upon waking up in the morning has been linked to a broad variety of factors such as personality, creativity, sleep behaviour and cognitive function. There have been conflicting findings as to whether dream recall is related more to the right or to the left hemisphere, and conflicting findings regarding the relationship of dream-recall frequency to handedness. We have found previously that right- and mixed-handers report having more dreams than left-handers, a finding more pronounced among adolescents than adults.

Processing emotion from the eyes: a divided visual field and ERP study.

The right cerebral hemisphere is preferentially involved in recognising at least some facial expressions of emotion. We investigated whether there is a laterality effect in judging emotions from the eyes. In one task a pair of emotionally expressive eyes presented in central vision had to be physically matched to a subsequently presented set of eyes in one or other visual hemifield (eyes condition).

Digit ratio (2D:4D), salivary testosterone, and handedness.

The length of the index finger relative to that of the ring finger, the 2D:4D ratio, has been taken to be a marker of the amount of testosterone (T) that was present in the foetal environment (Manning, Scutt, Wilson, & Lewis-Jones, 1998). It has also been suggested (Geschwind & Galaburda, 1987) that elevated levels of foetal T are associated with left-handedness and that adult levels of circulating T might relate to foetal levels (Jamison, Meier, & Campbell, 1993). We used multiple regression analyses to investigate whether there is any relationship between either left or right hand 2D:4D ratio and handedness.

Semantic errors in deep dyslexia: does orthographic depth matter?

Semantic errors of oral reading by aphasic patients are said to be comparatively rare in languages with a shallow orthography. The present report concerns three bilingual brain-damaged patients who prior to their stroke were fluent in both English, an orthographically deep language, and Welsh, an orthographically shallow language. On a picture-naming task, each patient made a similar proportion of semantic errors in the two languages.

Handedness in Great Britain.

Two large British databases of handedness assessed by writing hand at 10-11 years of age were analysed by geographical region. Left-handedness was found to vary significantly across regions according to one survey but not the other. In both data sets, left-handed writing was significantly more frequent in England than in Scotland and Wales combined.

Direction of hair whorl and handedness.

We recorded the direction of hair whorl rotation in samples of male right- and non-right-handers. The data corroborate those of Klar (2003) in showing equal numbers of clockwise and anti-clockwise whorls in non-right-handers but an excess of clockwise whorls in right-handers. The findings support the view that in some proportion of the population direction of coiling arises as a consequence of random events occurring during early (pre-natal) development of the nervous system, while in the remainder of the population there is a systematic bias towards a clockwise direction of rotation.

Visual laterality effects in readers of a deep and a shallow orthography.

Using a tachistoscopic split-field paradigm, hemifield asymmetry for single word recognition was examined in monolingual English speakers and in fluent bilingual English-Welsh speakers. A robust right hemifield advantage was found for both groups and both languages. Among bilinguals, the laterality index was significantly greater for Welsh than for English, supporting previous findings.

Facilitation of receptive and productive foreign vocabulary learning using the keyword method: the role of image quality.

Ellis and Beaton (1993a) reported that the keyword method of learning enhanced memory of foreign vocabulary items when receptive learning was measured. However, for productive learning, rote repetition was superior to the keyword method. The first two experiments reported here show that, in comparison with rote repetition, both receptive and productive learning can be enhanced by the keyword method, provided that the quality of the keyword images is adequate.

Dyslexia and across-hands finger localization deficits.

Two experiments on finger localization are reported. Experiment 1 compared children who were poor readers with two groups of children matched to poor readers for sex and either age (CA controls) or reading age (RA controls). The participant's hands were kept out of his or her sight in a semi-open box while the fingers of one hand were lightly touched by the experimenter.