Publications by authors named "Alan Bannister"
Article Synopsis
- The study investigated the distribution of Chlamydia trachomatis genotypes among men who have sex with men (MSM) at the Brighton GUM Clinic, focusing on correlations with HIV status and other clinical variables.
- Out of 1809 MSM participants, 112 (6.2%) tested positive for rectal Chlamydia, revealing 66 different genotypes with significant differences between HIV-negative and HIV-positive men.
- The findings showed a higher diversity of C. trachomatis strains within this population compared to other cities, with prevalent genotypes including G, E, and D, and distinct clusters of genotypes associated with HIV status.
Tenofovir disoproxil fumarate (TDF) has been anecdotally associated with isolated hypophosphatemia (HP) as well as proximal tubular toxicity and renal dysfunction in which HP has consistently been a feature. Consequently, routine phosphate measurements in TDF recipients have been recommended. We identified and compared the frequency of HP in TDF recipients with that in non-TDF recipients; assessed the reproducibility of HP; identified the incidence of renal dysfunction in hypophosphatemic patients; and evaluated associations between HP and host, HIV infection, or treatment factors.
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