Prevalence of transthyretin cardiac amyloidosis in patients with aortic stenosis.

Background: Transthyretin cardiac amyloidosis (ATTRCA) is a prevalent disease, and it can be associated with heart failure (HF), left ventricle hypertrophy (LVH), atrial fibrillation (AF), and aortic stenosis (AS).

Aim: The study aims to detect the prevalence of ATTRCA in the symptomatic AS population.

Method: A single-center prospective study screening for ATTRCA in patients diagnosed with symptomatic severe AS undergoing aortic valve (AV) intervention.

Eight weeks of aerobic exercise, but not four, improves insulin sensitivity and cardiovascular performance in young women.

Regular aerobic exercise has a significant impact on glucose metabolism and lipid profiles, contributing to overall health improvement. However, evidence for optimal exercise duration to achieve these effects is limited. This study aims to explore the effects of 4 and 8 weeks of moderate-intensity aerobic exercise on glucose metabolism, lipid profiles, and associated metabolic changes in young female students with insulin resistance and varying body mass, seeking to determine the optimal duration for physiological adaptations.

First Report from Saudi Arabia of Trimethylaminuria Caused by a Premature Stop Codon Mutation in the Gene.

Background: Trimethylaminuria (TMAU) is a rare recessive genetic disorder with limited global prevalence. To date, there have been no official reports of TMAU cases documented in Saudi Arabia.

Purpose: In this study, we developed a liquid chromatography-mass spectrometry (LC-MS) method for the analysis of trimethylamine (TMA) and Trimethylamine N-Oxide (TMAO) in urine and plasma samples for the first reported case of TMAU in Saudi Arabia.

Silent reactivation of Varicella Zoster virus in hemodialysis patients.: A management dilemma.

Objectives: To determine the seroprevalence of Varicella Zoster virus (VZV) immunoglobulin (Ig)G and IgM antibodies among hemodialysis patients (HDP). Additionally, the presence of VZV viral DNA has been investigated for possible reactivation status.

Methods: Sera from 265 individuals were collected and tested.

Metabolic signatures of combined exercise and fasting: an expanded perspective on previous telomere length findings.

Introduction: Aging is a complex process marked by a gradual decline in physiological function and increased susceptibility to diseases. Telomere length is frequently regarded as one of the primary biomarkers of aging. Metabolic profiles are key features in longevity and have been associated with both age and age-related diseases.

Factors Influencing Telehealth Adoption in Managing Healthcare in Saudi Arabia: A Systematic Review.

Background: The utilization of telehealth as an effective means to provide quality services is steadily rising across different tiers of the health system. However, advancing telehealth utilization relies on the current healthcare systems' infrastructure, policies, cultural factors, and utilization requirements can influence the utilization of telehealth within Saudi Arabia's healthcare system.

Purpose: This study seeks to systematically review the literature related to examining the factors influencing telehealth adoption and identifying the barriers and determinants of the use of telehealth in Saudi's healthcare system.

Teleradiology in Saudi Arabia: a national survey and retrospective review of associated MRI reports.

Background: Due to the recent evolution of telecommunications, it is now acknowledged that digital communication provides essential services for remote areas. Teleradiology allows the ability to obtain images at one site, send them over a distance, and view them remotely for diagnostic or consultation purposes.

Aim: The highlighted objectives include (a) the added value of the service, (b) user satisfaction, and (c) quality assurance according to global best practices and national quality standards.

Opioid Control for Patients With Sickle Cell Anemia in Emergency Departments in the Western Region of Saudi Arabia.

Introduction Sickle cell anemia (SCA) affects the Saudi Arabian population significantly, with 4.2% carriers and 0.26% affected.

Countering the Identified Barriers to Delivered Oral Care for Children With Special Healthcare Needs: A Narrative Review.

Children with Special Health Care Needs (SHCNs) have poor oral health as a result of structural and systemic barriers. These children frequently have limited access to dental treatment, a higher prevalence and incidence of dental problems, and worse oral hygiene than the rest of the population. This review aims to offer an understanding of the existing oral care barriers of children with SHCNs.

The Association Between Emotional Intelligence and Academic Performance of Dental Students at King Saud University, Riyadh, Saudi Arabia.

Introduction: Emotional intelligence (EI) is reported to be associated with better academic performance. However, few studies from the Middle East have assessed whether EI affects academic performance in dental students. The objective of this study was to evaluate the relationship between EI and academic performance in a sample of Saudi Arabian dental students.

Saudi Heart Association/National Heart Center/Saudi Arabian Cardiac Interventional Society/Saudi Society for Cardiac Surgeons/Saudi Cardiac Imaging Group 2023 TAVI Guidelines.

Saudi Arabia has seen a significant improvement in its healthcare system over the past four decades resulting in an increase in life-expectancy. Transcatheter aortic valve implantation (TAVI) has spread widely in Saudi Arabia and has become a routine procedure in many centers. The expanding clinical indications and the availability of the technology have made it possible for many large and intermediate centers all over the country to commence their own TAVI programs.

Exploring university students' nutrition literacy in Saudi Arabia: a cross-sectional survey.

Introduction: Improving individuals' nutrition literacy can be one way to promote healthy dietary behaviors, which lowers the incidence of non-communicable diseases. In Saudi Arabia, there is a limited information regarding nutrition literacy among students. Therefore, the purposes of this study was to investigate university students' nutrition literacy and identify its predictors in Saudi Arabia.

Social Media Use and Sleep Quality Among Secondary School Students in Aseer Region: A Cross-Sectional Study.

Background: Use of different social media platforms has increased radically over the past decade, emerging as an important part of adolescents and young people's everyday life. This might exert potential adverse effects on sleep quality and daytime performance of young adults.

Aim Of Study: To assess the relation between use of social media platforms and sleep quality among public secondary school students.

Endoscopy of Low BMI Patients Compared to Normal BMI Patients: A Study From the Aseer Region, Saudi Arabia.

Gastrointestinal (GI) endoscopies are essential for detecting and treating various digestive tract problems. While typically safe, these treatments can entail the risk of severe adverse events (SAEs), especially in individuals with a low body mass index (BMI). The current study aimed to evaluate whether post-endoscopy SAEs are more common in patients with low BMI and find risk factors for serious adverse outcomes in Saudi Arabian patients from Khamis Mushait, Aseer region, Saudi Arabia.

Joint Effects of Exercise and Ramadan Fasting on Telomere Length: Implications for Cellular Aging.

Aging is a fundamental biological process that progressively impairs the functionality of the bodily systems, leading to an increased risk of diseases. Telomere length is one of the most often used biomarkers of aging. Recent research has focused on developing interventions to mitigate the effects of aging and improve the quality of life.

Xylitol is prothrombotic and associated with cardiovascular risk.

Background And Aims: The pathways and metabolites that contribute to residual cardiovascular disease risks are unclear. Low-calorie sweeteners are widely used sugar substitutes in processed foods with presumed health benefits. Many low-calorie sweeteners are sugar alcohols that also are produced endogenously, albeit at levels over 1000-fold lower than observed following consumption as a sugar substitute.

An In Vitro Study: Does Adding Iodine Potassium Iodide and Cetrimide to Calcium Hydroxide Paste Enhance Its Antimicrobial Effect Against Oral Biofilms?

Objectives This study aimed to evaluate the antibiofilm effect of calcium hydroxide (CH), 0.5% iodine potassium iodide (IKI), and 0.5% cetrimide (CTR), alone and in combinations on one-week and three-week-old biofilms.

Retraction: Giant Unruptured Internal Carotid Artery Aneurysm.

[This retracts the article DOI: 10.7759/cureus.20423.

Retraction: Posterior Reversible Encephalopathy Syndrome: A Rare Complication in COVID-19.

[This retracts the article DOI: 10.7759/cureus.18426.

Microhardness and Gloss of a New CAD/CAM Hybrid Material Following Accelerated Aging and Coffee Immersion.

Purpose: To evaluate and compare the effect of accelerated aging and coffee immersion on the microhardness and gloss of a new computer-aided design and computer-aided manufacturing (CAD/CAM) hybrid material (Crystal Ultra) to those of contemporary restorative materials.

Materials And Methods: A total of 160 specimens (12 × 14 × 1 mm ± 0.05 mm) were obtained from IPS e.

Impact of Moderate Physical Activity on Inflammatory Markers and Telomere Length in Sedentary and Moderately Active Individuals with Varied Insulin Sensitivity.

Introduction: Physical activity-associated immune response plays a crucial role in the aging process. This study aimed to determine the impact of short-term moderate physical activity on cytokine levels, oxidative stress markers, and telomere length in lean/overweight young subjects.

Methods: Fasting blood samples were collected from 368 participants at Qatar Biobank.

Development of Biocompatible Ga(HPO) Nanoparticles as an Antimicrobial Agent with Improved Ga Resistance Development Profile against .

Ga(III) can mimic Fe(III) in the biological system due to its similarities in charge and ionic radius to those of Fe(III) and can exhibit antimicrobial activity by disrupting the acquisition and metabolism of Fe in bacterial cells. For example, Ga(NO) has been proven to be effective in treating chronic lung infections by () in cystic fibrosis patients in a recent phase II clinical trial. However, Ga(NO) is an ionic compound that can hydrolyze to form insoluble hydroxides at physiological pH, which not only reduces its bioavailability but also causes potential renal toxicity when it is used as a systemic drug.