Publications by authors named "Alamo Lourenco de Souza"
Influence of Agaricus blazei Murill polysaccharides on synthesis, stabilization, acute toxicity and antifungal activity of copper (II) oxide nanoparticles.
Álamo Lourenço de Souza Matheus da Silva Campelo Gabriel de Sousa Mesquita Augusto Feynman Dias Nobre Vitória Maria de Freitas Franco
Biometals
November 2024
Article Synopsis
- * The study involved synthesizing CuO nanoparticles, which were characterized for their properties and morphology, and then coated with Agaricus blazei Murill polysaccharides to improve stability and reduce toxicity.
- * The resulting coated nanoparticles demonstrated antifungal activity against Candida infections and lower toxicity in adult zebrafish, suggesting they could be promising candidates for topical treatments in medical applications.
Background: Clove volatile oil (CVO) and its major compound, eugenol (EUG), have anxiolytic effects, but their clinical use has been impaired due to their low bioavailability. Thus, their encapsulation in nanosystems can be an alternative to overcome these limitations.
Objectives: This work aims to prepare, characterize and study the anxiolytic potential of CVO loaded-nanoemulsions (CVO-NE) against anxious-like behavior in adult zebrafish (Danio rerio).