Publications by authors named "Alamgir Mirza"

Article Synopsis
  • * The Banff Working Group introduced a new classification for PyVAN based on viral load and interstitial fibrosis levels to better understand and categorize the condition.
  • * In a study of 124 kidney transplant patients, the new classification did not effectively predict risk for graft failure, with class 3 showing the worst outcomes but no significant differences between classes 1 and 2; additional factors like post-transplant timing and inflammation also played a role in graft failure.
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The APOL1 gene mutation is increasingly recognized as an import factor in living kidney donation. APOL1 gene variants prevalent in the African American population have been associated with increased risk of glomerulopathy. Shorter allograft survival is seen in transplants from donors who had 2 risk APOL1 gene alleles.

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Synopsis of recent research by authors named "Alamgir Mirza"

  • - Alamgir Mirza's research focuses on the diagnosis and implications of polyomavirus-associated nephropathy (PyVAN) in renal transplantation, emphasizing the need for accurate classification methods to better manage graft outcomes.
  • - His work includes exploring rare nephropathies, such as crystalglobulin-induced nephropathy linked to autoimmune conditions, showcasing the complexity of diagnosing kidney diseases in atypical presentations.
  • - Mirza examines the impact of genetic risk factors, particularly the APOL1 gene variants, highlighting their association with poorer transplant outcomes and increased recurrence rates of focal segmental glomerulosclerosis in African American kidney donors.