T analysis of the entire osteoarthritis initiative dataset.

While substantial work has been done to understand the relationships between cartilage T relaxation times and osteoarthritis (OA), diagnostic and prognostic abilities of T on a large population yet need to be established. Using 3921 manually annotated 2D multi-slice multi-echo spin-echo magnetic resonance imaging volume, a segmentation model for automatic knee cartilage segmentation was built and evaluated. The optimized model was then used to calculate T values on the entire osteoarthritis initiative (OAI) dataset composed of longitudinal acquisitions of 4796 unique patients, 25 729 magnetic resonance imaging studies in total.