Publications by authors named "Alain Ruffenach"
Background And Aim Of The Study: Because valve replacement for aortic stenosis (AS) remains a difficult surgical challenge in the presence of left ventricular dysfunction, the immediate and long-term outcomes, and evolution of left ventricular ejection fraction (LVEF) in this setting, were analyzed.
Methods: Forty-three consecutive patients with severe AS (valve area < or =1 cm2) and reduced LVEF (< or =40%) who underwent valve replacement surgery at the authors' institution between April 1998 and December 2003 and were studied retrospectively.
Results: Preoperative characteristics included: LVEF 33 +/- 6%, mean transaortic pressure gradient 46 +/- 13 mmHg, and aortic valve area 0.
Objective: Esmolol, an ultra-short-acting beta-blocker, is known to attenuate myocardial ischemia-reperfusion injury. The aim of this study was to compare the effects of esmolol and potassium on myocardial metabolism during continuous normothermic retrograde blood cardioplegia.
Methods: Forty-one patients operated on for isolated aortic valve stenosis were randomly assigned to continuous coronary infusion with either potassium or esmolol during cardiopulmonary bypass.
Article Synopsis
- The study aimed to assess how often patients experience no hyperlactatemia (NHL), immediate hyperlactatemia (IHL), or late hyperlactatemia (LHL) after cardiac surgery, along with their associated risk factors and outcomes.
- Conducted in a cardiac surgery ICU, the research involved 325 patients undergoing cardiopulmonary bypass (CPB) and measured lactate levels at various times post-surgery.
- The findings revealed that IHL upon ICU admission was linked to higher mortality rates compared to NHL and LHL, with specific risk factors identified, indicating that elevated lactate levels can predict patient outcomes following cardiac surgery.