Diamond burr debridement of calcific band keratopathy in 24 eyes of 22 horses.

Purpose: To evaluate the safety and effectiveness of diamond burr debridement (DBD) for the treatment of calcific band keratopathy (CBK) in horses.

Methods: Medical records from horses with CBK were reviewed over a period of 4 years. Diagnosis of CBK was based on slit-lamp examination findings, and DBD was performed on standing sedated horses.

Pyogenic granuloma of the cornea in a pony: Uncommon complication of corneal wound healing.

A 6-year-old miniature Shetland pony mare was referred for evaluation of a left corneal mass, which developed from the healing tissue of a corneal traumatic ulceration that had occurred 4 weeks previously. On gross examination, a spherical, smooth-surfaced, and pink-colored lesion of about 1 cm in diameter was protruding from the left palpebral fissure. Ophthalmic examination revealed that it was attached to the scar tissue of the cornea, and that one corpora nigra was adherent to the posterior face of corneal wounded area, without sign of uveitis.

Conjunctival calcinosis circumscripta in a dog: Treatment combining surgical resection and amniotic membrane grafting.

This report describes the clinical features, histopathology, and surgical treatment of a case of conjunctival calcification in a 5-month-old female English Setter, referred with a history of recurrent conjunctivitis in the right eye (OD). The ophthalmic findings were limited to multifocal white plaques embedded in a markedly inflamed conjunctiva of the eyelids and the anterior nictitating membrane OD. Calcification was suspected.

Corneal anesthesia associated with topical application of 2% lidocaine nonophthalmic gel to healthy canine eyes.

Objective: To assess the degree and duration of corneal anesthesia induced by topical application of 2% lidocaine gel to the healthy canine eye.

Animals: Nineteen adult Beagles free of ocular abnormalities.

Procedures: Baseline corneal touch threshold (CTT) was measured bilaterally with a Cochet-Bonnet aesthesiometer.

Subconjunctival nodule due to Setaria equina erratic migration in a horse: First case report.

An 18-month-old Arabian-English filly resident in southwest France was referred for evaluation of a conjunctival mass in the right eye (OD). A pink, solid, and mobile nodular formation, measuring approximately 1.2 × 0.

Congenital lacrimal fistula in two prim'Holstein calves.

Two 4- and 8-month-old prim'Holstein calves were presented for chronic epiphora. Examination of the affected eyes revealed an abnormal duct opening inferonasal to the medial canthus. A diagnosis of congenital lacrimal fistula was made based on conventional and computed tomographic-dacryocystography findings.

Changes in pupil size and intraocular pressure after topical application of 0.5% tropicamide to the eyes of dogs sedated with butorphanol.

Objective: To assess changes in pupil size and intraocular pressure (IOP) following topical application of a 0.5% tropicamide solution in the eyes of healthy butorphanol-sedated dogs.

Animals: 12 healthy adult Beagles.

Effect of topical application of 2% lidocaine gel on corneal sensitivity of clinically normal equine eyes.

Objective: To assess the degree and duration of corneal anaesthesia provided by topical application of a non-ophthalmic 2% lidocaine gel in horses.

Study Design: Experimental, 'blinded', randomized prospective study.

Animals: Twelve adult horses without relevant ocular abnormalities.

Effect of sedation with butorphanol on variables pertaining to the ophthalmic examination in dogs.

Objective: To evaluate whether sedation with intramuscular butorphanol can interfere with different variables of the ocular examination in dogs.

Animals: Twenty-two beagles without ophthalmic abnormalities.

Procedures: Each dog was examined 20 min prior to and again just before administration of butorphanol to establish baseline data.

Preliminary study of the safety and efficacy of medium-chain triglycerides for use as an intraocular tamponading agent in minipigs.

Purpose: To date, only silicone oils and gases have the appropriate characteristics for use in vitreo-retinal surgery as vitreous substitutes with intraocular tamponading properties. This preliminary study evaluated the safety and efficacy of medium-chain triglycerides (MCTs) for use as a tamponading agent in minipigs.

Methods: In 15 minipigs, 15 right eyes underwent vitrectomies followed by injection of MCT tamponade (day 1).

Submicroscopic deletions at 13q32.1 cause congenital microcoria.

Congenital microcoria (MCOR) is a rare autosomal-dominant disorder characterized by inability of the iris to dilate owing to absence of dilator pupillae muscle. So far, a dozen MCOR-affected families have been reported worldwide. By using whole-genome oligonucleotide array CGH, we have identified deletions at 13q32.

Corneal anesthesia following application of 0.4% oxybuprocaine hydrochloride ophthalmic solution to normal feline eyes.

Objective: To evaluate the loss and recovery of corneal sensitivity after instillation of 0.4% oxybuprocaine hydrochloride solution in the normal feline eye.

Animal Studied: Eighteen European shorthair cats free of ocular disease

Procedures: Baseline corneal touch threshold (CTT) readings were obtained bilaterally with a Cochet-Bonnet aesthesiometer prior to treatment.

Degree and duration of corneal anesthesia after topical application of 0.4% oxybuprocaine hydrochloride ophthalmic solution in ophthalmically normal dogs.

Objective: To assess the anesthetic efficacy and local tolerance of topically applied 0.4% oxybuprocaine ophthalmic solution to in dogs and compare its effects with those of 1% tetracaine solution.

Animals: 34 ophthalmically normal Beagles.

Florfenicol concentrations in ovine tear fluid following intramuscular and subcutaneous administration and comparison with the minimum inhibitory concentrations against mycoplasmal strains potentially involved in infectious keratoconjunctivitis.

Objective: To measure florfenicol concentrations in ovine tear fluid after IM and SC administration and determine minimum inhibitory concentrations (MICs) of florfenicol against field isolates of Mycoplasma organisms potentially involved in infectious keratoconjunctivitis.

Animals: 9 healthy adult Lacaune ewes.

Procedures: Animals received an IM and SC administration of florfenicol (20 mg/kg) in a 2-way crossover design.

Infectious sacroiliitis: a retrospective, multicentre study of 39 adults.

Background: Non-brucellar and non-tuberculous infectious sacroiliitis (ISI) is a rare disease, with misleading clinical signs that delay diagnosis. Most observations are based on isolated case reports or small case series. Our aim was to describe the clinical, bacteriological, and radiological characteristics of ISI, as well as the evolution of these arthritis cases under treatment.

Histopathologic features of canine distichiasis.

Objective: To describe the histologic features of canine distichiasis using excised tarsoconjunctival specimens that included roots of distichiatic cilia.

Procedures: The study group included 21 strips of cilia-bearing tarsoconjunctiva resected from 20 dogs with distichiasis. Eyelid tissue specimens were also collected from 11 euthanized dogs without distichiasis to serve as controls.

Clinical, electroretinographic and histomorphometric evaluation of the retina in sheep with natural scrapie.

Background: The retina is part of the diencephalon in a peripheral location and may be involved in prion diseases. Retinal function and structural changes were assessed in naturally scrapie-affected red face Manech ewes presenting the classical signs of the disease, and clinically healthy age-matched subjects for controls. Ophthalmic examination was done prior to electroretinography (ERG), which was carried out under conditions that allowed photopic and scotopic activities to be assessed.

Choroidal melanocytoma in a cat.

An 11-year-old male, neutered European cat was presented for anisocoria due to pupillary dilation in the right eye. Ophthalmic findings were restricted to this eye and consisted of a raised, darkly pigmented, retrolental mass associated with retinal detachment. Ultrasonography identified the mass lesion protruding into the vitreous cavity from the posterior pole of the eyeball and confirmed the detachment of the retina.

Keratoprosthesis with retrocorneal fixation: preliminary results in dogs with corneal blindness.

Objective: To evaluate the use and complications of a penetrating keratoprosthesis implantation in the management of corneal opacification in dogs.

Methods: A retrospective clinical study describes the indications for the surgical technique utilized and the outcomes of this procedure in 20 eyes of 19 dogs with blindness of corneal origin. A successful surgical outcome was defined as a clear keratoprosthesis optic and improvement or restoration of functional vision over a follow-up period ranging from at least 8 months to a maximum of 7 years.

Intraocular pharmacokinetics of intravenously administered marbofloxacin in rabbits with experimentally induced acute endophthalmitis.

Objective: To compare penetration of IV administered marbofloxacin in intraocular fluids of healthy and inflamed eyes in rabbits with endotoxin-induced endophthalmitis.

Animals: 35 pigmented rabbits.

Procedures: Endophthalmitis was induced in the right eye via intravitreal administration of Escherichia coli endotoxin.

Congenital orbital cysts of neural tissue in two dogs.

A 3-month-old English Cocker Spaniel and a 6-month-old miniature poodle presented with clinical signs related to an abnormal right eye since birth. In both dogs, the right globe could not be identified and was replaced by a fluctuant intraorbital mass covered by a vascularized mucous membrane. Ultrasonography demonstrated that both masses were cystic structures markedly larger in size than the normal contralateral globes.

Comparative effect of alfuzosin and tamsulosin on the contractile response of isolated rabbit prostatic and iris dilator smooth muscles: possible model for intraoperative floppy-iris syndrome.

Purpose: To compare the pharmacologic properties of tamsulosin and alfuzosin in isolated prostatic and iris dilator smooth muscle from pigmented rabbits.

Setting: UROsphere Laboratories, Université Paul Sabatier, Toulouse, France.

Methods: Prostatic and iris dilator smooth muscle strips were placed in organ baths.

Comparison of cytologic and histologic evaluations of the conjunctiva in the normal equine eye.

Objective: To describe the cells observed in conjunctival brush cytology (CBC) from normal horses and compare these findings with conjunctival structural histology so as to understand which cells are recovered from CBC.

Methods: This study was divided into three parts. (1) Conjunctival brush smears were collected from 20 healthy horses on both eyes and a differential count on 300 cells was carried out on May Grünwald-Giemsa (MGG) smears.

Ocular effects of topical 0.03% bimatoprost solution in normotensive feline eyes.

Objective: The current study was undertaken to evaluate the effects of topically applied bimatoprost, an ocular hypotensive lipid, on intraocular pressure (IOP) and pupil size (PS) in healthy cats.

Animal Studied: Nine European Shorthair cats free from clinically relevant ocular abnormalities were used in the study.

Procedures: Pretreatment baseline measurements of IOP and PS were obtained bilaterally at 8 am, 2 pm, and 8 pm for five consecutive days (days 1 to 5).