Stochastic Mechanochemical Description of a Bioinspired Polymerization Process.

We present a theoretical investigation of a polymerization process catalyzed by an enzyme. A structural model of enzyme, sliding along the polymer chain as a Brownian particle, is proposed, and a stochastic approach is employed to describe the kinetics of the whole process. The key point of this work is the coupling mechanics/chemistry obtained by assuming that (1) some rates of chemical reaction depend on the position of the enzyme with respect to the polymer chain and (2) the potential energy and the friction coefficient in the Langevin equation depend on the chemical state of the polymerizing complex.