Dynamics of a diffusive model for cancer stem cells with time delay in microRNA-differentiated cancer cell interactions and radiotherapy effects.

Understand the dynamics of cancer stem cells (CSCs), prevent the non-recurrence of cancers and develop therapeutic strategies to destroy both cancer cells and CSCs remain a challenge topic. In this paper, we study both analytically and numerically the dynamics of CSCs under radiotherapy effects. The dynamical model takes into account the diffusion of cells, the de-differentiation (or plasticity) mechanism of differentiated cancer cells (DCs) and the time delay on the interaction between microRNAs molecules (microRNAs) with DCs.

Dynamics of a cross-superdiffusive SIRS model with delay effects in transmission and treatment.

We investigate the dynamics of a SIRS epidemiological model taking into account cross-superdiffusion and delays in transmission, Beddington-DeAngelis incidence rate and Holling type II treatment. The superdiffusion is induced by inter-country and inter-urban exchange. The linear stability analysis for the steady-state solutions is performed, and the basic reproductive number is calculated.

Computer simulation of the dynamics of a spatial susceptible-infected-recovered epidemic model with time delays in transmission and treatment.

Background And Objective: In this work, we analyze the spatial-temporal dynamics of a susceptible-infected-recovered (SIR) epidemic model with time delays. To better describe the dynamical behavior of the model, we take into account the cumulative effects of diffusion in the population dynamics, and the time delays in both the Holling type II treatment and the disease transmission process, respectively.

Methods: We perform linear stability analyses on the disease-free and endemic equilibria.

A review on nonlinear DNA physics.

The study and the investigation of structural and dynamical properties of complex systems have attracted considerable interest among scientists in general and physicists and biologists in particular. The present review paper represents a broad overview of the research performed over the nonlinear dynamics of DNA, devoted to some different aspects of DNA physics and including analytical, quantum and computational tools to understand nonlinear DNA physics. We review in detail the semi-discrete approximation within helicoidal Peyrard-Bishop model and show that localized modulated solitary waves, usually called breathers, can emerge and move along the DNA.

Diffusive instabilities in a hyperbolic activator-inhibitor system with superdiffusion.

We investigate analytically and numerically the conditions for wave instabilities in a hyperbolic activator-inhibitor system with species undergoing anomalous superdiffusion. In the present work, anomalous superdiffusion is modeled using the two-dimensional Weyl fractional operator, with derivative orders α∈ [1,2]. We perform a linear stability analysis and derive the conditions for diffusion-driven wave instabilities.

Fractional formalism to DNA chain and impact of the fractional order on breather dynamics.

We have investigated the impact of the fractional order derivative on the dynamics of modulated waves of a homogeneous DNA chain that is based on site-dependent finite stacking and pairing enthalpies. We have reformulated the classical Lagrangian of the system by including the coordinates depending on the Riemann-Liouville time derivative of fractional order γ. From the Lagrange equation, we derived the fractional nonlinear equation of motion.

Energy transport in the three coupled α-polypeptide chains of collagen molecule with long-range interactions effect.

The dynamics of three coupled α-polypeptide chains of a collagen molecule is investigated with the influence of power-law long-range exciton-exciton interactions. The continuum limit of the discrete equations reveal that the collagen dynamics is governed by a set of three coupled nonlinear Schrödinger equations, whose dispersive coefficient depends on the LRI parameter r. We construct the analytic symmetric and asymmetric (antisymmetric) soliton solutions, which match with the structural features of collagen related with the acupuncture channels.