Publications by authors named "Alain Eric Dubart"

In the context of the introduction of advanced practice nurses in emergency departments (APNs), the Collège de Médecine d'Urgence du Nord-Pas-de-Calais teamed up with the Unité de Formation et de Recherche des Sciences de la Santé et du Sport at the University of Lille to conduct a survey of emergency department management teams, with the aim of gaining a better understanding of their needs. The results revealed a number of obstacles and levers to the implementation of APNs, and led to a better understanding of the patient pathways in these departments. As a result, the content of the university teaching program could be reviewed with a view to meeting the needs expressed in the field.

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  • Diagnosing acute heart failure (AHF) in elderly patients with acute dyspnea is challenging, prompting the study of various biomarkers for improved accuracy.
  • A multicenter study in France assessed the effectiveness of five biomarkers (NT-proBNP, hs-cTnI, ST2, galectin-3, CD146) in diagnosing AHF among 238 elderly patients over a four-year period.
  • While individual biomarker accuracies varied, NT-proBNP alone provided the best diagnostic accuracy (0.72), and combining the biomarkers did not significantly improve upon this.
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  • Management of first episodes of primary spontaneous pneumothorax (air in the chest cavity) is debated, with this study comparing simple aspiration and chest tube drainage as treatment methods.
  • The trial involved 402 adults aged 18-50 and measured lung expansion 24 hours post-treatment, finding a higher failure rate in the aspiration group (29%) compared to the chest tube group (18%).
  • Despite higher failure rates, the aspiration method resulted in less overall pain and fewer complications, with recurrence rates of pneumothorax being 20% for aspiration and 27% for drainage.
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The aim of the current study was to compare 2 equations to predict peak oxygen uptake (V̇Opeak) in obese women, according to their obesity class. 92 maximal cardiopulmonary exercise testing sets (CPET with initial and subsequent increments set to achieve an exercise duration between 8-12 min) were retrospectively analysed. These CPET were divided into 3 groups according to the women body mass indexes (BMI): class 1 (30 kg.

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We report the case of a 92-year old woman with congenitally corrected transposition of the great arteries (CCTGA). The case is remarkable as the CCTGA had remained undiagnosed until the diagnosis was made when the patient was aged 70 years, and had 10 pregnancies without heart failure.

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Introduction: Prothrombin complex concentrate (PCC) for reversal of vitamin K antagonist (VKA) is the main therapeutic option in cases of life-threatening bleeding. Clinical use of PCC is poorly documented.

Methods: We prospectively assessed PCC use in four French emergency departments during a two year period 2006-2008 before publication of French Guidelines.

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The purpose of this study was to develop a simple, convenient and indirect method for predicting peak oxygen uptake (VO2peak) from a sub-maximal graded exercise test (GXT), in obese women. Thirty obese women performed GXT to volitional exhaustion. During GXT, oxygen uptake and the power at RPE 15 (VO2peak) were measured, and VO2peak was determined.

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Background: Testing for pulmonary embolism often differs from that recommended by evidence-based guidelines.

Objective: To assess the effectiveness of a handheld clinical decision-support system to improve the diagnostic work-up of suspected pulmonary embolism among patients in the emergency department.

Design: Cluster randomized trial.

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The purpose was to assess the validity of predicting peak oxygen uptake (.VO(2)peak) from Ratings of Perceived Exertion (RPE)< or =15, during a graded exercise test (GXT), in obese women. Forty-three obese women performed GXT to volitional exhaustion.

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Introduction: Exercise has beneficial effects on obesity and diabetes treatments. However, obese subjects do not closely adhere to training programs probably because of the monotony of the continuous exercise that is frequently proposed. To increase adherence to training programs, intermittent exercise, which is less monotonous, may be more appropriate.

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Background: Little is known about the incremental value of real-time myocardial contrast echocardiography (MCE) as an adjunct to pharmacologic stress testing. This study was performed to evaluate the diagnostic value of MCE to detect abnormal myocardial perfusion by technetium Tc 99m sestamibi-single photon emission computed tomography (SPECT) and anatomically significant coronary artery disease (CAD) by angiography.

Methods: Myocardial contrast echocardiography was performed at rest and during vasodilator stress in consecutive patients (N = 120) undergoing SPECT imaging for known or suspected CAD.

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Background: Little is known about the diagnostic accuracy of quantitative real-time myocardial contrast echocardiography (MCE) as an adjunct to stress testing. This study was performed to evaluate the agreement between MCE and technetium 99m-sestamibi single photon emission computed tomography (SPECT) for detection of perfusion defects and to investigate whether quantitative assessment of myocardial perfusion can increase the diagnostic value of MCE.

Methods: MCE was performed at rest and during peak adenosine stress in 50 unselected patients undergoing SPECT imaging.

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Background: The presence of cyclic intensity variation during real-time myocardial perfusion imaging (RTPI) has been controversially discussed. We investigated whether cyclic intensity variation is systematically found during RTPI and whether such variations are related to regional functional parameters.

Methods: Intraoperative RTPI were obtained in 12 pigs before, during, and after left descending coronary artery occlusion with 60 mL/h SonoVue infusion.

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