Remission of nonparaneoplastic autoimmune retinopathy after minimal steroid treatment.

Purpose: To describe the clinical findings in a patient demonstrating recovery from nonparaneoplastic autoimmune retinopathy after a minimal course of steroid treatment.

Methods: Clinical presentation was documented, and paraclinical tests were obtained using Humphrey automated perimetry for visual fields, Western blotting for antiretinal antibodies, and electroretinography for evaluation of rod and cone function.

Results: Initial presentation revealed marked visual field deficits, electroretinographic dysfunction, and the presence of α-enolase autoantibodies.

Creutzfeldt-Jakob disease presenting with visual manifestations.

Background: Creutzfeldt-Jakob disease (CJD) is a rare and progressive degenerative disease of the central nervous system (CNS), characterized pathologically by spongiform changes in various CNS tissues. It most often presents with rapidly progressing dementia and cognitive decline, along with other neurologic findings that correspond to affected areas of the CNS. We present 5 sporadic cases of CJD presenting with visual manifestations, 2 of which were consistent with the Heidenhain variant, which predominantly affects the occipital lobe.

Giant cell arteritis presenting with aortic aneurysm, normal erythrocyte sedimentation rate, and normal C-reactive protein.

Case Report: We report on an extremely rare case of giant cell arteritis (GCA) presenting without elevated erythrocyte sedimentation rate or C-reactive protein level, with aortic root involvement, and in the absence of typical clinical findings.

Comments: The clinical signs and symptoms as well as the laboratory investigations involved in the diagnosis of GCA are discussed.

Comparison of in vitro toxicity of single vs double exposures of indocyanine green in human retinal pigment epithelial cell cultures.

Purpose: To compare the in vitro effect of a single brief indocyanine green (ICG) exposure with a double exposure on retinal pigment epithelial (RPE) cells.

Design: In vitro laboratory experimental study.

Methods: Human ARPE-19 cells were exposed to a single dilute ICG exposure (0.

Development of macular hole in the early postoperative period following pneumatic retinopexy.

Pneumatic retinopexy is a minimally invasive procedure used to repair uncomplicated superior rhegmatogenous retinal detachments. Macular holes have been reported in only 6 cases as a rare sequel to this procedure. The development of macular hole in a patient in the early perioperative period following pneumatic retinopexy is described.

Comparison of the in vitro toxicity of indocyanine green to that of trypan blue in human retinal pigment epithelium cell cultures.

Purpose: To compare the in vitro toxicity of indocyanine green (ICG) to that of trypan blue (TB) in human retinal pigment epithelium cell cultures. The use of ICG and TB in macular hole surgery is discussed.

Design: In vitro cell biology experimental study.