Inclusion of calcium phosphate does not further improve in vitro and in vivo osteogenesis in a novel, highly biocompatible, mechanically stable and 3D printable polymer.

At a time of unpredictable challenges for health, one trend is certain: there is an exceedingly high demand for functional implants, particularly bone grafts. This has encouraged the emergence of bone tissue engineering substitutes as an alternative method to conventional bone grafts. However, the current approaches in the field face several limitations that have prevented the ultimate translation into clinical settings.

Synthesis, Characterization, and 3D Printing of an Isosorbide-Based, Light-Curable, Degradable Polymer for Potential Application in Maxillofacial Reconstruction.

Although emergence of bone tissue engineering techniques has revolutionized the field of maxillofacial reconstruction, the successful translation of such products, especially concerning larger sized defects, still remains a significant challenge. Light-curable methacrylate-based polymers have ideal properties for bone repair. These materials are also suitable for 3D printing which can be applicable for restoration of both function and aesthetics.

Physical properties and biocompatibility effects of doping SiO and TiO into phosphate-based glass for bone tissue engineering.

Phosphate glass is continuing to gain more attention as potential bone substitutes. The ternary (PO-CaO-NaO) is investigated in terms of both physical properties and biocompatibility by doping different percentages of SiO and TiO. Two groups were prepared; the first has different percentages of TiO and SiO, whereas the second group compositions have 5 mol% TiO and 5 mol% SiO being added to compensate the network-forming oxide PO and the network-modifying oxide CaO.

Three-dimensional Printing in Maxillofacial Surgery: Hype versus Reality.

Three-dimensional printing technology is getting more attention recently, especially in the craniofacial region. This is a review of literature enlightening the materials that have been used to date and the application of such technology within the scope of maxillofacial surgery.

Zinc and strontium based phosphate glass beads: a novel material for bone tissue engineering.

Degradable phosphate-based glasses that contain strontium, zinc and calcium were investigated to examine their function as an osteoconductive material. Glass beads of the general formula of (PO)-(NaO)-(TiO)-(CaO)-(SrO) or (ZnO) were prepared by a melt quench technique followed by milling and spheroidisation. After performing x-ray diffraction on all the samples for glass structure evaluation, glass bead size distribution was initially measured by a scanning electron microscope (SEM).