Physiology and immunology of the adrenergic anti-inflammatory pathway.

The adrenergic anti-inflammatory pathway represents a critical intersection between the nervous and immune systems, modulating the body's response to inflammation through the action of catecholamines on adrenergic receptors. This review explored the physiology underlying this pathway, focusing on the mechanisms by which the sympathetic nervous system influences immune function. We delved into the roles of specific adrenergic receptors, primarily the beta-adrenergic receptors, in mediating anti-inflammatory effects, highlighting the involved molecular signaling pathways.

Assessing the hepatoprotective effects of hesperidin on liver-associated disorders in albino rats with experimentally induced obesity and type II diabetes: A histological and biochemical study.

Unlabelled: Hesperidin (HSP) has multiple beneficial effects in verities of clinical situations including type 2 diabetes mellitus (T2DM).

Aim: Determination of curative effects of HSP on the liver in T2DM rats through biochemical and histopathological studies.

Methods: Animals.

Prevalence of hepatitis E virus in Egyptian children presented with minor hepatic disorders.

Unlabelled: Hepatitis E virus (HEV) is considered as one of the common causes of particular hepatitis in developing countries. It is transmitted in a fecal-oral manner. It causes sporadic infections and large epidemics.

Interleukin-18 expression in rheumatoid artheritis synovial tissue and its relation to disease activity.

The study investigates the expression and function of interleukin-18 (IL-18) in synovial tissue (ST) of patients with rheumatoid arthritis (RA). IL-18 and IL-18 receptors (IL-18R) mRNA expression was detected by reverse transcription-polymerase chain reaction (RT-PCR). Expression of IL-18 at protein level was analyzed by western blotting technique.