Publications by authors named "Alaa A A Mohamed"
Background And Aim: The data about the role of regulatory B cells (Breg) in Behcet Disease (BD) are scarce. We aimed to evaluate the frequency of total B lymphocytes and Breg cells in different BD phenotypes and therapies attempting to unravel their function.
Methods: This cross-sectional study included 35 BD patients and 39 healthy controls (HCs).
Article Synopsis
- * Researchers stimulated B cells and other immune cells with different types of IFN and validated a new testing method for tetherin (CD317), a protein that indicates IFN activity, in both a discovery cohort and a longitudinal validation cohort involving SLE patients and healthy controls.
- * The results revealed that tetherin expression on memory B cells was significantly linked to SLE diagnosis, disease activity, and the prediction of future clinical flares, suggesting it could serve as a useful biomarker for managing SLE
Objectives: This study aims to correlate subclinical echocardiographic features with the clinical, laboratory, and therapeutic profiles of the patients to characterize risks for systemic lupus erythematosus (SLE) cardiac diseases.
Methods: The study included 59 SLE patients. Demographic data, disease characteristics, and current therapies were recorded, and the anthropometric measurements and routine laboratory tests were performed.