Arabic version of Skindex-16: translation and cultural adaptation, with assessment of reliability and validity.

Background: Quality-of-life is increasingly recognized as an important measure in dermatology; however, most currently available dermatologic quality-of-life measures were originally created for the English language. Skindex-16 being one, is a self-administered questionnaire covering the symptoms, emotions and functioning aspects.

Objectives: Our aim was to translate into Arabic and culturally adapt Skindex-16 following the international guidelines for cross-cultural adaptation of health-related quality-of-life measures.

A retrospective study of some clinical and epidemiological features of impetigo patients seen in dermatology clinic in the eastern province of saudi arabia.

Background: Impetigo is a common contagious superficial skin infection, most frequently seen in children.

Objectives: To determine the clinical and epidemiological features of impetigo patients seen in the dermatology clinic of King Fahd Hospital of the University (KFHU).

Methods: This is a retrospective study of impetigo patients seen in the dermatology clinic at KFHU, Al-Khobar, Saudi Arabia, during the period January 1990 to December 2001.

Normal coordinate analyses and barrier to internal rotation of nitroso- and nitroazides.

The conformational and structural stability of nitrosoazide NNN-N=O and nitroazide NNN-NO2 were investigated by DFT-B3LYP and ab initio MP2 calculations with 6-311++G** basis set. From the calculations, nitrosoazide was predicted to exist predominantly in the planar trans (NNN and N=O groups are trans to each other) structure with high trans-cis rotational barrier of about 11 kcal mol-1 as a result of pronounced conjugation between the azide group and the N=O bond. The NO2 rotational barrier in nitroazide was predicted from the symmetric potential function to be of about 7 kcal mol-1.

Conformational stability and normal coordinate analyses for 1-halovinyl azides CH2=CX-NNN (X is F, Cl and Br).

The conformational behavior of 1-halovinyl azides CH2=CX-NNN (X=F, Cl and Br) were investigated by DFT-B3LYP and ab initio MP2 calculations with the 6-311++G** basis set. The molecules were predicted to exist predominantly in the trans (the vinyl CH2=CH- and the azide -NNN groups are trans to each other) conformation. The relative energy between cis and trans were calculated to decrease in order: bromide>chloride>fluoride.

Theoretical potential functions and vibrational analysis for halocarbonyl azides CXO-NNN (X=F, Cl and Br).

The structural stability of halocarbonyl azides CXO-NNN (X=F, Cl and Br) was investigated by DFT and MP2 calculations using the 6-311++G** basis set. From the calculations, the molecules were found to have an s-cis<--> s-trans conformational equilibrium with cis being the lower -energy form. Full energy optimizations were carried out for the transition states and the minima at the B3LYP/6 -311++G** and MP2/6 -311++G** levels, from which the rotational barriers were calculated to be of the order 8-10 kcal x mol(-1).

Focal dermal hypoplasia -- oral and dental findings.

This report describes the case of an 8-year-old girl with focal dermal hypoplasia. As well as deformities affecting her hands and feet she had marked facial asymmetry, one diminutive eye and coloboma affecting the other. Intraorally, the patient had papillomas at the base of the tongue and tonsils.

Managing bruxism and temporomandibular disorders using a centric relation occlusal device.

This article discusses the rationale, indications, and fabrication of the centric relation occlusal (CRO) device in the management of bruxism and temporomandibular disorders. Five methods of fabricating occlusal devices are briefly discussed. Two methods, preferred by the authors, are discussed in detail, including the laboratory phase.

Monocyte chemotactic protein expression in allergy and non-allergy-associated chronic sinusitis.

Objective: Chronic sinusitis (CS) is characterized by inflammatory mucosal thickening and polyp formation with a predominantly eosinophilic infiltrate. Chemokines are a novel group of inflammatory mediators capable of attracting specific inflammatory cell populations. Monocyte chemotactic proteins (MCP) are a subfamily of chemokines (MCP-1, MCP-2, MCP-3, and MCP-4) that share a number of functional properties including chemotactic activity for eosinophils.

Expression of IgE heavy chain transcripts in the sinus mucosa of atopic and nonatopic patients with chronic sinusitis.

We have recently shown the increased mRNA expression of interleukin (IL)-4 and IL-13 in sinus biopsies from allergic subjects with chronic sinusitis (ACS), whereas only IL-13 mRNA was elevated in biopsies obtained from nonallergic subjects with chronic sinusitis (NCS). In the lymph nodes and spleen, these cytokines may promote IgE production through transcriptional activation of the germline IgE heavy chain promoter, an event which precedes immunoglobulin isotype switching to IgE in B cells. We hypothesized that local expression of IL-4 and/or IL-13 might act by inducing germline IgE heavy chain transcript expression locally in the sinus mucosa of chronic sinusitis patients.

Interleukin-4, interleukin-5, and granulocyte-macrophage colony-stimulating factor receptor expression in chronic sinusitis and response to topical steroids.

Chronic sinusitis and its associated eosinophilic infiltrate are believed to be mediated, at least in part, by the upregulation of Th-2 cytokines, including interleukin-4, interleukin-5, and granulocyte-macrophage colony-stimulating factor (GM-CSF). Interleukin-4 is involved in IgE production and in eosinophil recruitment through upregulation of vascular cell adhesion molecule-1. Interleukin-5 and GM-CSF are involved in eosinophil growth and survival.

Hyperlipidemia and obesity among diabetics at jubail miiltary hospital.

Objective: Evaluate the pattern of dyslipidemia and obesity among diabetics, attending the Primary Care Clinic.

Subjects And Methods: All diabetics (282) registered in the Primary Care Clinic of the Armed Forces Hospital at King Abdulaziz Naval Base, Jubail, Eastern Saudi Arabia, were interviewed by primary care doctors. Weight and height were recorded; fasting blood glucose and cholesterol levels were measured after 12-hour fasting.

Parasitic and bacterial infestation among food handlers in jubail, eastern region of saudi arabia.

Objective: To evaluate the prevalence of parasitic and bacterial infestations among food handlers.

Design: Retrospective study.

Setting: Food handlers working in the Military food serving facilities in Jubail (Eastern Province of Saudi Arabia).