; unveiling the cause, spread, and molecular basis of a novel coriander leaf blight disease in Egypt.

L. faced a new and previously undocumented leaf blight disease for the first time. This disease manifests initially as small, circular, or irregular brown spots on older leaves, which gradually expand and merge into dark brownish blotches over time.

Antioxidant and antimicrobial activities of methanolic extract and its phytochemical characterization.

Methanolic extract from was investigated for its phytochemical content, antioxidant, and antimicrobial properties against phytopathogenic fungi and bacteria. Phytochemical analysis revealed the presence of saponin, tannins, and alkaloids with 1.25%, 18.

Identifying multidrug-resistant organisms in diabetic foot ulcers: a study of risk factors and antimicrobial resistance genes.

This study aims to evaluate the antibiotic susceptibility profiles of bacterial isolates from DFU patients, identify the prevalence of MDROs, and identify specific risk factors contributing to these infections to inform effective antibiotic treatment strategies. This prospective cohort study included 187 DFU patients from March 2023 to February 2024 at King Khalid Hospital, Saudi Arabia. The exclusion criteria were nondiabetic ulcers, specific infections, tumours, or recent antibiotic use.

Correction: Shehabeldine et al. Antimicrobial, Antibiofilm, and Anticancer Activities of Essential Oil Nanoemulsion. 2023, , 5812.

In the original publication [...

Effect of arbuscular mycorrhizal fungi on physiological, bio-chemical and yield characters of wheat plants (Triticum aestivum L.) under drought stress conditions.

This experiment was conducted to study the effect of inoculation with arbuscular mycorrhizal fungi (AMF) as an ecofriendly strategy on physiological, biochemical and yield characters of wheat plants. Our results showed a significant decrease in chlorophyll a and b as well as the maximum quantum efficiency of PSII (Fv/Fm) in wheat plants under drought conditions compared to control in the two seasons. Drought stress significantly reduced relative water content (RWC%) in the stressed plants compared with the control.

Anticancer, antimicrobial, insecticidal and molecular docking of sarcotrocheliol and cholesterol from the marine soft coral Sarcophyton Trocheliophorum.

The anticancer, antimicrobial, and insecticidal activities of sarcotrocheliol (1) and cholesterol (2) obtained from the soft coral Sarcophyton trocheliophorum (S. trocheliophorum) were intensively studied. According to this study, both compounds 1 and 2 showed potential cytotoxicity towards the human colorectal carcinomaHCT-116 (IC 10.

Awareness of Colorectal Cancer Preventive Measures Among Residents of Riyadh.

Background Colorectal cancer (CRC) poses a significant challenge to healthcare providers. Spreading awareness, providing preventive measures, and implementing screening programs are essential for detecting and halting the progression of the disease and decreasing the mortality associated with this type of malignancy. This study aimed to assess public knowledge and awareness of colorectal cancer preventive measures and screening programs among residents of Riyadh, Saudi Arabia, and also to design better healthcare interventions or policy development.

Unveiling the (L.) Hook medicinal bioactivities: phytochemical analysis, antibacterial, antibiofilm, and anticancer activities.

Commonly used antimicrobial agents are no longer effective due to their overuse or misuse. In addition, many medicinal plant extracts can combat infectious diseases due to their main active constituents or secondary metabolites. The current study aimed to assess the bioactivities of (LN) leaf extract (LE) against different multi-drug resistant (MDR) () isolates.

Biomedical Waste Management Knowledge among Dental Students and Private Dental Practitioners of Alkharj, Saudi Arabia.

Introduction: Improper handling of biomedical waste causes health hazards. Dental practitioners and students as health care professionals should know about biomedical waste management from its generation to disposal. This will prevent associated risk and cross-infection.

Awareness and Knowledge of Ionizing Radiation in Common Radiological Investigation and Associated Risks Among Medical and Applied Medical Sciences Students at Majmaah University.

Aim: This study aims to evaluate the awareness and knowledge of ionizing radiation in common radiological investigations, as well as the associated risks, among medical and applied medical sciences students at Majmaah University in Majmaah, Saudi Arabia.

Materials And Methods: This cross-sectional study involved 209 participants who completed an anonymous electronic questionnaire consisting of 21 questions. Participants were categorized based on demographic characteristics and assessed for their awareness and knowledge of radiation and its associated risks.

Discontinuation of Tyrosine Kinase Inhibitor Therapy and Treatment Free Remission (TFR) in Chronic Myeloid Leukemia: Successful Achievement of TFR in More Than Two-Third of Patients in a Real-World Practice.

Background: Discontinuation of TKI therapy and treatment-free remission (TFR) have become new goals for chronic-phase chronic myeloid leukemia (CP-CML). The aim of this study was to estimate the TFR post discontinuation of TKI therapy at 3 tertiary-care centers.

Patients And Methods: CP-CML patients aged ≥16 years who had an attempt to discontinue TKI therapy till June 2022, were eligible.

Antibacterial, antifungal, and phytochemical properties of ethanolic extract.

The research into the use of plants as plentiful reservoirs of bioactive chemicals shows significant potential for agricultural uses. This study focused on analyzing the chemical composition and potency of an ethanolic extract obtained from the aerial parts (leaves and stems) of against potato pathogenic fungal and bacterial pathogens. The isolated fungal isolates were unequivocally identified as and based on morphological characteristics and internal transcribed spacer genetic sequencing data.

Melanin Synthesized by the Endophytic AKW: A Multifaceted Biomolecule with Antioxidant, Wound Healing, and Selective Anti-Cancer Activity.

Introduction: This study explores the potential of the endophytic fungus Aureobasidium pullulans AKW for melanin production and its anticancer activity.

Method: We report a significant achievement: AKW synthesized 4.89 g/l of melanin in a simple fermentation medium devoid of tyrosine, a precursor typically required for melanin biosynthesis.

Biomedical Promise of Aspergillus Flavus-Biosynthesized Selenium Nanoparticles: A Green Synthesis Approach to Antiviral, Anticancer, Anti-Biofilm, and Antibacterial Applications.

This study utilized to produce selenium nanoparticles (Se-NPs) in an environmentally friendly and ecologically sustainable manner, targeting several medicinal applications. These biosynthesized Se-NPs were meticulously characterized using X-ray diffraction (XRD), Fourier-transform infrared (FT-IR) spectroscopy, transmission electron microscope (TEM), and UV-visible spectroscopy (UV), revealing their spherical shape and size ranging between 28 and 78 nm. We conducted further testing of Se-NPs to evaluate their potential for biological applications, including antiviral, anticancer, antibacterial, antioxidant, and antibiofilm activities.

Foliar Application of Rhizobium leguminosarum bv. viciae Strain 33504-Borg201 Promotes Faba Bean Growth and Enhances Systemic Resistance Against Bean Yellow Mosaic Virus Infection.

The bean yellow mosaic virus (BYMV) is one of the most serious economic diseases affecting faba bean crop production. Rhizobium spp., well known for its high nitrogen fixation capacity in legumes, has received little study as a possible biocontrol agent and antiviral.

Optimization of pullulan production by Aureobasidium pullulans using semi-solid-state fermentation and artificial neural networks: Characterization and antibacterial activity of pullulan impregnated with Ag-TiO nanocomposite.

This study presents a novel and efficient approach for pullulan production using artificial neural networks (ANNs) to optimize semi-solid-state fermentation (S-SSF) on faba bean biomass (FBB). This method achieved a record-breaking pullulan yield of 36.81 mg/g within 10.

Narrative review on nanoparticles based on current evidence: therapeutic agents for diabetic foot infection.

Diabetes's effects on wound healing present a major treatment challenge and increase the risk of amputation. When traditional therapies fail, new approaches must be investigated. With their submicron size and improved cellular internalisation, nanoparticles present a viable way to improve diabetic wound healing.

Unravelling the Antimicrobial, Antibiofilm, Suppressing () and Virulence Genes, Anti-Inflammatory and Antioxidant Potential of Biosynthesized Silver Nanoparticles.

: Urinary tract infections [UTIs] are considered the third most known risk of infection in human health around the world. There is increasing appreciation for the pathogenicity of Gram-positive and Gram-negative strains in UTIs, aside from fungal infection, as they have numerous virulence factors. : In this study, fifty urine samples were collected from patients suffering from UTI.

Fully Characterized Effective Bacteriophages Specific against Antibiotic-Resistant , the Causative Agent of Dental Abscess.

: is a primary pathogen responsible for dental abscesses, which cause inflammation and pain when trapped between the crown and soft tissues of an erupted tooth. Therefore, this study aims to use specific phages as an alternative method instead of classical treatments based on antibiotics to destroy multidrug-resistant bacteria for treating dental issues. : In the current study, twenty-five bacterial isolates were obtained from infected dental specimens; only five had the ability to grow on bile esculin agar, and among these five, only two were described to be extensive multidrug-resistant isolates.

Favorable outcome of non-myeloablative allogeneic transplantation in adult patients with severe sickle cell disease: A single center experience of 200 patients.

Allogeneic hematopoietic stem cell transplant (HSCT) for adults with severe sickle cell disease (SCD) is potentially curative but not commonly utilized therapy due to complications such as graft failure (GF) and organ toxicity. Herein, we are reporting our long-term outcome data of non-myeloablative (NMA) HSCT in adults with severe SCD with emphasis on factors predicting event free survival (EFS). Adults with severe SCD undergoing NMA match-related donor allogeneic HSCT from 2015 to 2021 with at least 12 months of follow-up were included.