Improved recovery of cardiac auscultation sounds using modified cosine transform and LSTM-based masking.

Obtaining accurate cardiac auscultation signals, including basic heart sounds (S1 and S2) and subtle signs of disease, is crucial for improving cardiac diagnoses and making the most of telehealth. This research paper introduces an innovative approach that utilizes a modified cosine transform (MCT) and a masking strategy based on long short-term memory (LSTM) to effectively distinguish heart sounds and murmurs from background noise and interfering sounds. The MCT is used to capture the repeated pattern of the heart sounds, while the LSTMs are trained to construct masking based on the repeated MCT spectrum.

Comparison of fracture resistance of fiber-reinforced post and core with different cementation techniques: in vitro study.

Objective: The current study aimed to inspect the fracture resistance of fiber post to canal dentin using a different technique of cementation.

Materials And Methods: 60 sound single-rooted central incisors with comparable size and length were stored in normal saline. Each tooth was immersed in 5% sodium hypochlorite (NaOCl).

The influence of a gluten-free diet on health-related quality of life in individuals with celiac disease.

Background: Adherence to a gluten-free diet (GFD) and food insecurity (FI) may influence health-related quality of life (HRQOL) in individuals with celiac disease (CD). This study aimed to investigate the association between adherence to a GFD, FI, and HRQOL in individuals with CD.

Methods: This cross-sectional study included 97 adults (mean age: 34 ± 9 years) diagnosed with CD.

Biomedical invasive pressure sensor coatings: calibration and waveform perspectives.

The biocompatibility of invasive biomedical sensors is a fundamental issue in the design of implanted sensors. Therefore, the unique packaging of the sensor is a crucial design procedure that must be performed and evaluated correctly. Under steady-state measurements, the sensor calibration can be done quickly, and the corresponding errors and loss in the sensor's sensitivity, because of the packaging material, can be compensated easily.

Relapse of Aplastic Anemia with Majority Donor Chimerism (Donor-Type Aplasia) Occurring Late after Bone Marrow Transplantation.

There have been sporadic reports of the development of delayed disease recurrence after bone marrow transplantation for severe aplastic anemia despite sustained majority or full donor chimerism. This is termed "donor-type aplasia" (DTA). We describe the management and outcome of 11 pediatric patients from 8 institutions in Europe, the United States, and the Middle East who developed DTA at a mean of 35 months post-transplant.

Incidence and risk factors of bacterial infections in children following autologous hematopoietic stem cell transplantation: Single-center experience from Jordan.

Bacterial infection is a serious sequela following AHSCT; however, limited data are available regarding pediatric recipients, especially in developing countries. We retrospectively analyzed the incidence and risk factors of bacterial infections during the first 100 days after AHSCT in children at KHCC in Amman, Jordan between January, 2005 and September, 2013. A total of 65 patients were identified, with median age of four yr (1-17).

Hematopoietic stem cell transplantation from non-sibling matched family donors for patients with thalassemia major in Jordan.

There are limited data on the outcome of patients with thalassemia receiving HSCT from non-sibling matched family donors. Of the 341 patients with thalassemia major that underwent donor search at our center from January 2003 to December 2011, 236 (69.2%) had fully matched family donor of which 28 patients (8.

Bone Mineral Density and Growth in Children Having Undergone Liver Transplantation With Corticosteroid-Free Immunosuppressive Protocol.

Background: Children post-liver transplantation (post-LTX) are at risk of growth delay and decreased bone mineral density (BMD) secondary to corticosteroid (CS) therapy and suboptimal intake of nutrients important for bone health. The pediatric LTX program at Stollery Children's Hospital introduced a CS-free LTX regimen in 2003. This retrospective study investigated whether the implementation of a CS-free protocol resulted in improvements in BMD (dual x-ray absorptiometry) and growth following LTX.

Incidence and risk factors for cytomegalovirus (CMV) reactivation following autologous hematopoietic stem cell transplantation in children.

There are limited data on the incidence of CMV reactivation following autologous HSCT (AHSCT) in children. We retrospectively reviewed the incidence and risk factors for CMV reactivation in 72 children who received AHSCT. Twenty-two patients (31%) had positive CMV antigenemia at a median of 23 days (12-31) following transplant.

Hematopoietic stem cell transplantation of an adolescent with neurological manifestations of homozygous missense PRF1 mutation.

Individuals with biallelic truncating PRF1 mutations typically present with fulminant early-onset familial hemophagocytic lymphohistiocytosis (FHL). We report a 19-year-old male with a 5-year history of recurrent fever and headaches progressing to refractory seizures. Brain imaging revealed multiple ring enhancing lesions.

Safety and feasibility of granulocyte colony-stimulating factor (G-CSF) primed bone marrow (BM) using three days of G-CSF priming as stem cell source for pediatric allogeneic BM transplantation.

There are limited data on the optimal dosing and schedule of G-CSF priming prior to BM harvest. We evaluated the safety and efficacy of three days of G-CSF of primed BM from related pediatric donors. Forty-five children were treated.

Risk factors, characteristics and outcomes of necrotizing enterocolitis in late preterm and term infants.

Objective: To identify the risk factors, characteristics and outcomes of necrotizing enterocolitis (NEC) at our institution.

Study Design: A retrospective case-control analysis of the charts of all late preterm and term infants, who had NEC of Bell's stage ≥ II from 1995 to 2009, along with infants of the same gestational age. Thirty-two late preterm infants had NEC meeting criteria and 128 late preterm and term infants were chosen as matched controls.

Allogeneic hematopoietic stem cell transplantation for infants with idiopathic myelofibrosis.

IMF is a rare disease in children that can present during infancy and has a protracted course. The only known curative approach for this disease in adult patients is allogeneic HSCT. There are very few reports describing the long-term outcome of young children following stem cell transplantation for IMF.

Statistical performance evaluation of ECG transmission using wireless networks.

This paper presents simulation of the transmission of biomedical signals (using ECG signal as an example) over wireless networks. Investigation of the effect of channel impairments including SNR, pathloss exponent, path delay and network impairments such as packet loss probability; on the diagnosability of the received ECG signal are presented. The ECG signal is transmitted through a wireless network system composed of two communication protocols; an 802.

Hematopoietic stem cell transplantation for children with primary immunodeficiency diseases: single center experience in Jordan.

HSCT can be curative for many PID. Little is known about the outcome of HSCT for patients with PID in the developing countries. We retrospectively reviewed all children with PID who received HSCT at KHCC in Jordan between August 2003 and October 2011.

Risk adopted allogeneic hematopoietic stem cell transplantation using a reduced intensity regimen for children with thalassemia major.

Background: Patients with thalassemia in developing countries have limited access to safe transfusions, regular medical care and chelation therapy. Although allogeneic hematopoietic stem cell transplantation (HSCT) can offer a curative approach, there are limited data on the use of this procedure in developing countries.

Procedure: Forty-four patients underwent a risk adopted HSCT from matched related family donor in Jordan.

High-Dose Therapy and Autologous Hematopoietic Progenitor Cells Transplantation for Recurrent or Refractory Hodgkin's Lymphoma: Analysis of King Hussein Cancer Center Results and Prognostic Variables.

Purpose. to evaluate the outcome of patients with Hodgkin's lymphoma who underwent autologous transplantation at KHCC bone marrow transplant program. Patients and Methods.

Unrelated cord blood transplantation can restore hematologic and immunologic functions in patients with Chediak-Higashi syndrome.

CHS is a rare hereditary fatal disease, if not treated. APs occur in 85% of patients and are usually the main cause of mortality, and HSCT from HLA-matched related and unrelated donors is the only effective treatment for CHS and prevents recurrences of APs. We reviewed the records of three patients with CHS who underwent UCBT at KHCC.

Infections with the 2009 H1N1 influenza virus among hematopoietic SCT recipients: a single center experience.

We retrospectively reviewed medical records of 39 hematopoietic SCT (HSCT) recipients who presented at our hospital between 1 October 2009 and 31 January 2010 with the 2009 H1N1 influenza infection. The median age at presentation was 13.8 years (range: 3.

Telemetry design of a vital sign recording system.

Blood pressure, respiratory rate, body temperature, and pulse rate are vital signs that under certain pathological conditions require continuous monitoring. In this paper we present a novel design of a system that embeds these signals into a single waveform that can be transmitted without the need for time or frequency division multiplexing. The system depends on changing the frequency of a square wave oscillator.

Haploidentical stem cell transplantation as a salvage therapy for cord blood engraftment failure in a patient with Fanconi anemia.

A 7-year-old male with Fanconi Anemia who developed primary graft failure following one antigen-mismatched unrelated cord blood transplantation and a nonradiation-based conditioning, underwent a second hematopoietic stem cell transplantation (HSCT) from his 2-loci mismatched haploidentical father, using a nonradiation-based regimen, 79 days after the first HSCT. A sustained hematological engraftment was achieved at 9 days post-second HSCT. At 15 months post-second HSCT; the patient demonstrated normal blood counts, sustained donor chimerism, and no evidence of GVHD.

Spectral investigations of intraluminal impedance signals.

In this paper, an investigation of the spectral characteristics of intraluminal impedance signals using local Hilbert-Huang transform is presented. The impedance waveform may contain three main events: reflux event, swallow event and baseline region corresponding to no activity. The three events are analysed using local Hilbert-Huang transform to characterize the frequency contents of each event.

Extraction of arterial blood pressure signal from intraluminal impedance signals.

Multichannel intraluminal procedure provides information about the esophagus status, reflux occurrence, and clearance mechanism. The study of the impedance signals has been concentrated on the study of reflux patterns and clearance mechanisms. However, there are a number of sources that results in the variations seen in impedance signal.