Resin infiltration for white spot lesions: An in vitro experimental trial.

Objective: To evaluate the aesthetic outcome by varying the duration allowed for infiltrant penetration when treating white spot lesions with resin infiltration.

Design: An in vitro, experimental randomised study.

Methods: Artificially created white spot lesions (WSLs) were induced on 100 extracted anterior teeth (T1).

Allogeneic Hematopoietic Cell Transplantation with Non-Myeloablative Conditioning and Post-Transplant Cyclophosphamide Prophylaxis in Patients with Reduced Systolic Function.

Post-transplantation cyclophosphamide (PTCy) has become standard of care for graft-versus-host disease (GVHD) prophylaxis after allogeneic hematopoietic cell transplantation (alloHCT), allowing for expanded donor options. However, there is scant literature examining outcomes of patients with reduced systolic function receiving PTCy. The present study aimed to describe our experience in performing alloHCT in patients with reduced systolic function, including their nonrelapse mortality (NRM), overall survival (OS), and cumulative incidence of early cardiac events (ECEs).

Pregnancy Considerations in the Multidisciplinary Care of Patients with Pulmonary Arterial Hypertension.

Pulmonary arterial hypertension (PAH) is a vasoconstrictive disease of the distal pulmonary vasculature resulting in adverse right heart remodeling. Pregnancy in PAH patients is associated with high maternal morbidity and mortality as well as neonatal and fetal complications. Pregnancy-associated changes in the cardiovascular, pulmonary, hormonal, and thrombotic systems challenge the complex PAH physiology.

Molar Incisor Hypomineralization: Awareness among Postdoctoral Dental Residents: A Cross-Sectional Study.

Background: Molar incisor hypomineralization (MIH) is the presentation of an enamel defect, where incisors and one (or more) molars are affected. Identifying MIH is significant in restoring its visual defect and avoiding pain or other consequences of this condition. The present cross-sectional study aimed to evaluate the awareness, ability, and confidence in identifying MIH among postgraduate residents in the state of Nevada.

Prevalence of hyperdontia, hypodontia, and concomitant hypo-hyperdontia.

Background/purpose: Anomalies in human dentition are some of the most common occurrences of congenital abnormalities. Present study aimed to determine the prevalence of hypodontia, hyperdontia and concomitant hypo-hyperdontia (CHH) among patients attending the University of Nevada, Las Vegas (UNLV) School of Dental Medicine clinics.

Materials And Methods: Retrospective search was conducted on patients' clinical notes in AxiUm™.

Cardiovascular Emergencies in Pregnancy.

Heart disease in pregnancy may manifest as acute coronary syndromes, decompensated valvular disease, and acute heart failure. These disease processes may represent progression of preexisting disease versus newly developed disease resulting from the physiologic changes of pregnancy. Early recognition of clinical presentations, judicious use of diagnostic studies, and multidisciplinary management of patient and fetal considerations can lead to optimal outcomes in this unique patient subset.

The Impact of Non-nutritive Sucking on the Risk for Sleep-disordered Breathing in Children.

Purpose: Sleep-disordered breathing (SDB) is not uncommon in children. The purposes of this study were to investigate the relationship between non-nutritive sucking (NNS) and the risk of SDB in children as well as assess the effect of infant feeding practices on SDB.

Methods: Eighty-four healthy four- to 12-year-old children were categorized either as high or low risk for SDB based on the Pediatric Sleep Questionnaire (PSQ).

Consil bioactive glass particles enhance osteoblast proliferation and maintain extracellular matrix production in vitro.

Bioactive glasses are used clinically as bone implant materials as they are able to bond directly with bone. Studies in dogs have demonstrated the utility of Consil Bioglass synthetic bone graft particulate, a commercially available bioactive glass formulation, as a bone substitute for repair of bony defects. We evaluated the effect of Consil particles (500 microg/mL) on osteoblast proliferation and extracellular matrix (ECM) production at the cellular level in vitro.

Avocado soybean unsaponifiables (ASU) suppress TNF-alpha, IL-1beta, COX-2, iNOS gene expression, and prostaglandin E2 and nitric oxide production in articular chondrocytes and monocyte/macrophages.

Objective: To evaluate the effects of avocado soybean unsaponifiables (ASU) on proinflammatory mediators in chondrocytes and monocyte/macrophage-like cells.

Design: To determine the dose response of ASU, chondrocytes (5 x 10(5) cells/well) were incubated at 5% CO(2), 37 degrees C for 72 h with (1) control media alone or (2) ASU at concentrations of 0.3, 0.