Publications by authors named "Al-Shehri S"

In this investigation, blue-emitting carbon nanodots (B.CNDs) with exceptional color purity were successfully synthesized from fresh fig fruit using a one-step pyrolysis method. These B.

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Although there is ample proof of the advantages of infection prevention and Control (IPC) in acute-care hospitals, there is still some questions about the efficacy of IPC interventions for multidrug-resistant organisms (MDROs), and there is a need for the development of evidence-based practices. No healthcare facility has found a single effective technique to reduce MDRO. However, a multicomponent intervention that included improved barrier protection, chlorhexidine bathing, microbiological monitoring, and staff involvement significantly decreased the likelihood of infection in the patient surroundings with multidrug-resistant organisms.

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Background: Epidemiological evidence has shown that human papillomavirus (HPV) is the most frequent cause of sexually transmitted infection, and vaccination is an essential measure to prevent associated diseases and complications. This study aimed to assess the HPV vaccine uptake and its associated factors as well as HPV vaccine hesitancy by female healthcare workers (HCWs) in Saudi Arabia.

Methods: This online, questionnaire-based, cross-sectional study involved female HCWs in Saudi Arabia between July and October 2022.

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  • * A recent study surveyed 3,238 adults in Saudi Arabia, finding that around 41% had undergone plastic surgery, with breast augmentation being the most common procedure.
  • * Factors influencing the decision for surgery included a focus on appearance enhancement, with the majority of participants being young, married women, many of whom had low income and a basic education.
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Thyrotoxic crisis (thyroid storm) is a severe form of hyperthyroidism. It has a wide range of symptoms, including cardiovascular manifestations that can be life-threatening and require prompt management. Cardiac manifestations of thyroid storm include hypertension, tachycardia, congestive heart failure, cardiac ischemia, and atrial fibrillation.

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Purpose: Epidemiologically, cervical cancer is the fourth most commonly diagnosed cancer among females globally and the third most commonly diagnosed gynecological cancer in Saudi Arabia. Screening is an important measure to prevent it. The current study aimed to assess, epidemiologically, female healthcare workers' (HCWs) utilization of cervical cancer screening services and its association with their beliefs about cervical cancer and the screening test, as well as their personal characteristics.

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Artificial intelligence (AI) applications have transformed healthcare. This study is based on a general literature review uncovering the role of AI in healthcare and focuses on the following key aspects: (i) medical imaging and diagnostics, (ii) virtual patient care, (iii) medical research and drug discovery, (iv) patient engagement and compliance, (v) rehabilitation, and (vi) other administrative applications. The impact of AI is observed in detecting clinical conditions in medical imaging and diagnostic services, controlling the outbreak of coronavirus disease 2019 (COVID-19) with early diagnosis, providing virtual patient care using AI-powered tools, managing electronic health records, augmenting patient engagement and compliance with the treatment plan, reducing the administrative workload of healthcare professionals (HCPs), discovering new drugs and vaccines, spotting medical prescription errors, extensive data storage and analysis, and technology-assisted rehabilitation.

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Diabetes mellitus (DM) is one of the most common diseases worldwide. DM may disrupt hormone regulation. Metabolic hormones, leptin, ghrelin, glucagon, and glucagon-like peptide 1, are produced by the salivary glands and taste cells.

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Background: Diabetes mellitus [DM] is the most prevalent disease that affects modern human life in Saudi Arabia. People with DM must have a comprehensive understanding of the nature, risk factors, complications, and treatment methods to mitigate complications.

Aim: The aim of the study is to assess diabetic patient awareness of complications and their effect on treatment compliance in the Asir region of Saudi Arabia.

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  • Hypothyroid patients on levothyroxine face challenges with medication adherence during Ramadan due to fasting, leading to a study on the best administration times.
  • The study found that compliance was lowest when taking the medication 3-4 hours after the iftar meal, while most patients preferred taking it 30 minutes before iftar.
  • Results showed a significant increase in TSH and FT4 levels after Ramadan, but the timing of levothyroxine intake did not affect these hormone levels, suggesting flexibility in administration timing.
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Background/aim: DNA methylation is the most studied epigenetic modification in cancer. Ten-eleven translocation enzymes (TET) catalyze the oxidation of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC) in the DNA. In the current research, we aimed to evaluate the role of 5-hmC and TET enzymes in non-small cell lung cancer (NSCLC) patients and their possible association with outcomes.

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Exposure to lead (Pb) is associated with serious health problems including hepatorenal toxicity. Apigenin is a natural-sourced flavonoid with promising antioxidant and anti-inflammatory effects. In this research, we investigated the potential protective role of apigenin against lead acetate (PbAc)-induced hepatorenal damage.

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Introduction Menopause is an important period in a woman's life. It is the permanent cessation of menses for 12 months or more. Menopause can develop over a long period of time.

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Purpose: This study primarily aimed to evaluate the effectiveness of computational data management and analytical software for establishing departmental diagnostic reference levels (DRLs) for computed tomography (CT) scanning in clinical settings, and monitor achievable doses (ADs) for CT imaging, particularly during the coronavirus disease 2019 (COVID-19) era. Secondarily, it aimed to correlate these standards with national and international benchmarks.

Patients And Methods: This ambidirectional cohort study enrolled 4668 patients (6419 CT-based examinations) who visited King Fahd Hospital of the University from May 25, 2021, to November 4, 2021.

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Plaques can form across different parts of the aorta, from the aortic arch to the thoracic and abdominal aorta. Aortic arch atheroma, however, is highly associated with cerebrovascular insults due to their dislodgement. Although no concise management protocol has been defined for dealing with such presentations, antiplatelet agents and anticoagulants are most frequently used.

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Background: Several safety-related accidents occur in the laboratories because of insufficient regulations, inappropriate implementation of safety measures, or unawareness attitude and practices toward safety precautions. Thus, establishment of efficient regulations and safe habits toward workplace safety is crucial to prevent or minimize such accidents. Here we investigate the levels of laboratory safety awareness among undergraduate medical science students and laboratory workers at major hospitals in Taif, Saudi Arabia.

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  • Thyroid storm (TS) is a serious medical emergency mostly triggered by Graves' disease (GD), and can occur after immune reconstitution therapy with the drug alemtuzumab in patients with multiple sclerosis.
  • A case is highlighted involving a 39-year-old woman who developed TS due to GD triggered by alemtuzumab, and she was treated with antithyroid medications followed by a thyroidectomy.
  • There is some evidence suggesting that GD caused by alemtuzumab may be less aggressive than typical GD, but it's crucial for doctors to be vigilant about the risk of severe complications like TS, which necessitate quick treatment.
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Background: Disseminated nocardiosis still causes significant morbidity and mortality and is often caused by Nocardia asteroides, N. basiliensis, and N. farcinica and are often treated with trimethoprim-sulfamethoxazole (TMP-SMX).

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The mRNA turnover and ribosome assembly are facilitated by Mrt4 protein from . In present study, we are reporting the cloning, expression and homogeneous purification of recombinant Mrt4. Mrt4 is a 236-amino-acid-long nuclear protein that plays a very crucial role in mRNA turnover and ribosome assembly during the translation process.

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The aim of this study was to estimate the radiation effective doses for operators of nuclear moisture density gauges that are used in pavement construction in the road industry in Saudi Arabia from 2016 to 2019. The effective doses of 278 workers were estimated using thermoluminescent dosemeters (TLD-700). The analysis of the dosimetry data revealed that the mean annual effective dose for all workers averaged over the study period was 0.

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Objective: Anxiety disorders are among the leading causes of disability worldwide. Generalised anxiety disorder (GAD) is characterised as a state of excessive anxiety for six months or more, which is difficult to control and is not triggered by a specific situation or stressor. This study aims to assess the relationship between GAD and multiparity.

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Grape seed extract (GSE) is a natural source of polyphenolic compounds and secondary metabolites, which have been tested for their possible antimicrobial activities. In the current study, we tested the antibacterial and antifungal activities of aqueous GSE and the biosynthesized silver nanoparticles loaded with GSE (GSE-AgNPs) against different pathogens. The biosynthesized GSE-AgNPs were assessed by UV spectroscopy, dynamic light scattering (DLS), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), and gas chromatography/mass spectrometry (GC/MS).

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Workers in the mining industry face the problem of radiation exposure from naturally occurring radioactive materials. Thus, this study aimed to estimate a Hp (10) doses for mine workers in the phosphate mining industry in Saudi Arabia. The personal dose equivalent [Hp (10)] of 606 mine workers in the phosphate mining industry in Saudi Arabia were obtained from 2016 to 2019 using thermoluminescent dosemeters (TLDs).

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Purpose: Minimum segment width (MSW) plays a fundamental role in the shaping of optimized apertures and creation of segments of varying sizes and shapes in complex radiotherapy treatment plans. The purpose of this work was to study the effect of MSW on dose distribution in patients planned with VMAT for various treatment sites using dose volume histogram (DVH) analysis.

Materials And Methods: For the validation of optimum MSW, 125 clinical treatment plans were evaluated.

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Introduction: Massive haemoptysis refers to coughing and losing a huge amount of blood in a 24-hour period. It's a life-threatening condition with high mortality rate.

Case Presentation: We report a rare case of massive haemoptysis in a 60-year-old female patient who had aortic coarctation repair 30 years ago.

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