Maternal experience of intimate partner violence, maternal depression, and parental stress are not associated with child telomere length in Bangladesh.

Shorter telomere length (TL) is associated with an increased risk for developing chronic or age-related diseases in adults. The process of telomere shortening is accelerated in response to stress and is well characterized in adult populations from high-income countries. Prior studies suggest the relationship between stress, shorter TL, and disease risk initiates in early life.

Association of Knowledge and Attitude Toward Antibiotic Use and Resistance With Self-Medication Practice of Antibiotics Among Bangladeshi Private University Teachers: A Cross-Sectional Study.

Background And Aims: Antibiotic resistance is increasing globally and regionally, posing a significant public health concern. This study aimed to assess knowledge and attitude toward antibiotic use and the prevalence of self-medication and its association with the knowledge and attitude toward antibiotic use and resistance among private university teachers in Bangladesh.

Methods: This quantitative, cross-sectional study utilized a convenience sampling technique and included 509 respondents.

Pectin-Zein-IPA nanoparticles promote functional recovery and alleviate neuroinflammation after spinal cord injury.

Introduction: Spinal cord injury (SCI) impairs the balance of gut microbiomes, which further aggravates inflammation in the injured areas and inhibits axonal regeneration. The intestinal microbiome plays an important role in SCI and regulating intestinal microbiome promotes SCI repair. However, current studies have shown that indole-3 propionate (IPA), a metabolite of gut bacteria, can promote axonal regeneration.

evaluation of missense SNPs in cancer-associated Cystatin A protein and their potential to disrupt Cathepsin B interaction.

Cystatin A (CSTA) functions as a cysteine protease inhibitor by forming tight complexes with the cathepsins. Pathogenic mutations in the CSTA gene can disrupt this interaction, potentially leading to physiological ailments. In this study, eight bioinformatics tools (SIFT, PolyPhen-2, PROVEAN, P-Mut, MutPred2, SNAP2, SNPs & GO, and PHD-SNP) were implemented to analyze non-synonymous SNPs from the dbSNP database.

PHLPP1 depletion promotes tumorigenesis and stemness in triple-negative breast cancer cells through AKT signaling.

Breast cancer, particularly triple-negative breast cancer (TNBC), is a major cause of women's mortality, and effective treatment options are still lacking due to the absence of known mechanisms and biomarkers. Therefore, unveiling novel molecular mechanisms to identify potential biomarkers is urgently needed to ensure an effective TNBC treatment. In this study, we investigated the role of PHLPP1, a tumor suppressor gene, in the tumorigenesis and induction of cancer stem cells in TNBC using publicly available data and experimental protocols.

Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity.

Background: Obesity is associated with dysregulated metabolism and low-grade chronic inflammation in adipose tissue (AT). Immune cells, including macrophages, T cells, and neutrophils, infiltrate the AT and secrete proinflammatory cytokines to exacerbate the AT inflammation. RNA-Seq analysis of AT immune cells isolated from mice fed a high-fat diet (HFD) versus normal fat diet (ND) identified a panel of genes that were markedly downregulated, including sialic acid-binding Ig-like lectin E (siglec-E), in HFD compared to ND mice.

Urban water supply risks assessment under tropical climate.

The urban water supply system in tropical countries faces various physical risks, including pipe failures due to aging, material type, soil conditions, flooding, extreme weather events, and traffic loads. This study focuses on urban water supply risks for eight zones of Brunei-Muara district. A risk assessment using a data-driven matrix reveals Zones D2 and D6 as very high-risk areas, experiencing monthly average leaks of 880 and 471, respectively.

Multi-targeted nanogel drug delivery system alleviates neuroinflammation and promotes spinal cord injury repair.

Spinal cord injury (SCI) is significantly hampered by an inflammatory microenvironment, prompting continued efforts in drug development to address inflammation. Research shows that quercetin (Que) exhibits excellent performance in reducing inflammation and neuroprotection. However, its application is limited by poor solubility, notable side effects, and the unique pathophysiology of the spinal cord.

Epidemiological Aspects of Notified Sexually Transmitted Infections and a Review of the Current Surveillance System in Tabuk, Saudi Arabia.

Objective Our study aimed to identify the epidemiological patterns of notified sexually transmitted infections (STIs) in the Tabuk Region, Saudi Arabia, and to review the existing STI surveillance system. Methods We conducted a retrospective cross-sectional study, extracting STI surveillance data from the Health Electronic Surveillance Network Plus (HESN Plus) database. All notified STI cases (100%) reported to the Department of Public Health, Ministry of Health in the Tabuk Region, and available in the HESN Plus database until 19 November 2024, were included in the study.

Recent advances in the role of neuroregulation in skin wound healing.

Neuroregulation during skin wound healing involves complex interactions between the nervous system and intricate tissue repair processes. The skin, the largest organ, depends on a complex system of nerves to manage responses to injury. Recent research has emphasized the crucial role of neuroregulation in maximizing wound healing outcomes.

Factors Influencing Knowledge and Attitudes towards Second-Hand Smoking Exposure Among University Students: An Exploratory Study.

Despite extensive global research on second-hand smoking (SHS) exposure, there is a noticeable lack of studies focusing on the knowledge and attitudes of university students in Bangladesh. This cross-sectional study aimed to address this gap by assessing the levels of knowledge and attitudes towards SHS exposure among university students in Bangladesh. Utilizing a convenience sampling technique, data were collected from 383 university students, encompassing socio-demographic information, as well as knowledge and attitude-related inquiries.

A new approach to children's work that prioritises resilience, well-being and agency: emerging findings from a 'cash plus' intervention in Bangladesh.

Background: Criticism of mainstream approaches to child labour is widespread and well-established. The Child Labour Action Research in South and Southeast Asia (CLARISSA) Cash Plus pilot sought to address these critiques through an innovative programme that prioritised the development of household resilience and well-being, and through increasing household capacity to make alternative choices around children's work.

Research: Funded by the UK's Foreign, Commonwealth and Development Office, this pilot delivered unconditional cash transfers (UCTs) and needs-based case management and community mobilising across an entire slum neighbourhood in Dhaka, Bangladesh.

Dynamic event-triggered tolerant containment control protocol for discrete multiagent systems based on finite index policy iteration algorithm.

For tolerant containment control of multi-agent systems, considering the challenges in modeling and the impact of actuator faults on system security and reliability, a finite index dynamic event-triggered policy iteration algorithm is proposed. This algorithm only requires input and output data, without relying on system models, and simultaneously considers the faults and energy consumption issues to improve the system reliability and save energy consumption. The conditions are provided to demonstrate the convergence and optimality of the algorithm, including a convergence speed, that is, the number of iterations required for convergence is finite.

Prevalence and associated risk factors of musculoskeletal disorders among information technology (IT) professionals: A systematic review.

Musculoskeletal disorders (MSDs) are a growing concern among information technology (IT) professionals. Understanding the specific risk factors associated with MSDs among employers, occupational health practitioners, and IT professionals may reveal effective preventive measures. The aim of this study was to examine the prevalence and identify the risk factors associated with MSDs among IT professionals.

Selective lead ion sensing via cotton pad-based NaEDTA capped AuNPs: A smartphone-assisted colorimetric method.

Herein, NaEDTA-capped AuNPs specifically designed for selective smartphone-assisted colorimetric detection are synthesized and characterized. NaEDTA-capped AuNPs was synthesized and characterized by UV-Visible spectroscopy, ATR, Raman, XRD, SEM and EDX. The calculated activation energy of the produced nanoparticles was 0.

An empirical study on logistic service quality, customer satisfaction, and cross-border repurchase intention.

Domestic e-retailers acknowledge logistics service quality (LSQ) as a critical success factor in business excellence. However, exponential growth in cross-border e-commerce (CBEC) requires a re-evaluation of the relationship between LSQ and consumers repurchase intention. By integrating the technology acceptance model, this study investigates the impact of LSQ on repurchase intention based on the LSQ (experience)-satisfaction-repurchase intention consequence chain.

Disability and depression among stroke survivors attending rehabilitation facilities at three designated tertiary care hospitals in Bangladesh: A cross-sectional study.

Background: Poststroke depression (PSD) is a highly prevalent and serious mental health condition affecting a significant proportion of stroke survivors worldwide. While its exact causes remain under investigation, managing PSD presents a significant challenge.

Aim: This study aimed to evaluate the prevalence and predictors of depression among Bangladeshi stroke victims.

Assessment of Bacteriological Quality and Antibiotic Resistance in Locally and Industrially Produced Ice Creams: A Study on Probiotic Incorporation for Enhanced Safety and Health Benefits in Kushtia City, Bangladesh.

Ice creams are consumable foods that have the potential to be used as probiotic carriers. The purpose of this study was to evaluate the bacteriological quality (i.e.

The Role of Laparoscopy in Managing Impalpable Undescended Testes in a Tertiary Hospital.

One of the most prevalent congenital defects in boys is undescended testes. Ultrasound is commonly employed to locate the testis in cases of impalpable testes, which frequently yields false-negative results. Laparoscopy has gained widespread acceptance recently for managing impalpable testes.

Understanding mental health challenges and associated risk factors of post-natural disasters in Bangladesh: a systematic review.

Background And Objectives: Natural disasters are harmful occurrences caused by the Earth's geological and meteorological processes. Bangladesh is recognized as one of the country's most vulnerable to natural disasters. Therefore, the people of Bangladesh remain at high risk of natural disasters.

Isolation, Structure Elucidation, and Bioactivity Evaluation of Two Alkaloids From H. Stem: A Traditional Medicinal Spice and Its Chemico-Pharmacological Aspects.

Bangladesh is endowed with an abundance of excellent medicinal plant resources. A well-known traditional medicinal plant H. from the Piperaceae family is rich in bioactive phytochemicals that have antidiarrheal, antimicrobial, analgesic, antioxidant, anticancer, and cytotoxic effects.