A short history of methods used to measure bathing beach water quality.

The enumeration of fecal indicators of bathing beach water to determine quality have been used since the mid-20th century. In the 1930s and as late the 1970s, the Most Probable Number procedure for estimating microbial densities in water was in general use. The most probable number procedure was replaced as a method of choice by the membrane filter procedure.

Statistical approaches to developing a multiplex immunoassay for determining human exposure to environmental pathogens.

There are numerous pathogens that can be transmitted through water. Identifying and understanding the routes and magnitude of exposure or infection to these microbial contaminants are critical to assessing and mitigating risk. Conventional approaches of studying immunological responses to exposure or infection such as Enzyme-Linked Immunosorbent Assays (ELISAs) and other monoplex antibody-based immunoassays can be very costly, laborious, and consume large quantities of patient sample.