Publications by authors named "Akunna Francess Ujuagu"
Article Synopsis
- A new fluorogenic peptide probe called BIQ-FiLuP, designed for detecting HIV-1 TAR RNA, uses a deep-red emissive dye to enhance fluorescence signaling.
- This probe replaces a specific amino acid in the Tat peptide with a benzo[c,d]indole-quinoline (BIQ) dye, achieving a significant increase in light emission when TAR RNA is present.
- BIQ-FiLuP can accurately distinguish between different types of inhibitors in fluorescence assays, minimizing optical interference and allowing simultaneous use with green-emissive dyes for comprehensive testing of various fluorescent compounds.
Spectral pretreatments, such as background removal from Raman big data, are crucial to have a smooth link to advanced spectral analysis. Recently, we developed an automated background removal method, where we considered the shortest length of a spectrum by changing the scaling factor of the background spectrum. Here, we propose a practical way to correct the systematic error caused by noise from measurements.
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