Establishment of Pathogen-Free Colonies Under Laboratory Conditions for the Vector Competence Studies.

, the primary vector of , is also considered to transmit , , and spp. These claims are based on pathogen detections rather than experimental validation. To confirm vector competence, sterile ticks must acquire pathogens from infected hosts and transmit them to other hosts.

Treatment Adherence, Internalised Stigma and Recovery Among Individuals Diagnosed With Schizophrenia in Eastern Turkey.

Introduction And Aim: This study aimed to assess the relationship between treatment adherence, internalised stigma, recovery and the mediating effect of internalised stigma on these relations in individuals diagnosed with schizophrenia.

Method: This study was conducted using a cross-sectional design. A purposive sample of 107 individuals diagnosed with schizophrenia receiving psychiatric outpatient care at outpatient clinics and community mental health services (CMHC) affiliated with SBU Van research and education hospital was recruited for this study.

Recovery Notion of Individuals With Schizophrenia and Their Families in Eastern Turkey: A Qualitative Study.

Purpose: To determine the recovery notion among individuals with schizophrenia and their families in Eastern Turkey.

Method: A descriptive phenomenological study was performed. Individual in-depth interviews were conducted, and data were analyzed using Braun and Clarke's thematic analysis.

Experimental infection of purebred Saanen goats high pathogenicity and virulence of Babesia aktasi.

Small ruminant babesiosis remains a neglected disease despite causing significant economic losses to sheep and goat herds in many regions around the world. The pathogenesis and clinical manifestations of ovine babesiosis are well-known, but there is a lack of information regarding caprine babesiosis. Since the discovery of the first Babesia spp.

Assessment of pathogenicity in goats: implications for transmission dynamics and host resistant.

, commonly associated with ovine babesiosis, poses a significant threat to sheep health, often resulting in severe clinical manifestations and high mortality rates. However, the impact of on goats has remained uncertain, prompting us to investigate its pathogenicity in caprine hosts. Experimental infections using -infected blood inoculation and infected tick infestation, were conducted on spleen-intact (n=5) and splenectomized (n=5) goats.

Treatment experiences of women diagnosed with substance use disorder in eastern Turkey: A qualitative study.

Purpose: The aim of this study was to determine the addiction treatment experiences of women with substance use disorders in eastern Turkey with qualitative approach.

Methods: The study was conducted using the phenomenological method, one of the qualitative study methods. Purposive sampling was used to select the sample for the study.

Risk of recurrent ventricular tachyarrhythmia following the occurrence of a first ventricular arrhythmic event in patients with a primary prevention implantable cardioverter-defibrillator.

Background: There are limited data on clinical and arrhythmic outcomes after a first ventricular tachyarrhythmia (VTA) in heart failure (HF) patients who receive a primary prevention implantable cardioverter-defibrillator (ICD).

Objective: This study was designed to quantify the burden of and to identify risk factors for recurrent VTA in this population and to evaluate the risk of all-cause mortality associated with recurrent VTA.

Methods: The study comprised 789 patients who experienced VTA following primary prevention ICD implantation in 5 ICD trials (MADIT-II, MADIT-RISK, MADIT-CRT, MADIT-RIT, RAID).

Door-to-Diuretic Time is related to length of hospital stay independent of diuretic dose among acute decompensated heart failure patients.

Background: Acute decompensated heart failure (ADHF) treatment guidelines recommend initial dosages for diuretic drugs but lack guidance on treatment timing. Recent evidence indicates that faster treatment, or shorter Door-to-Diuretic (D2D) Time, may improve outcomes.

Objectives: This study assessed how diuretic dose, D2D Time, and their interaction affect hospital length of stay.

Risk stratification for ventricular tachyarrhythmia in patients with nonischemic cardiomyopathy.

Introduction: The implantable cardioverter defibrillator reduces mortality among patients with heart failure (HF) due to ischemic heart disease. Clinical trial data have called into question the benefit of an ICD in patients with HF due to nonischemic cardiomyopathy (NICM). We developed a risk stratification score for ventricular tachyarrhythmia (VTA) among patients with NICM receiving a primary prevention ICD.

Coronary artery disease and the risk of life-threatening cardiac events after age 40 in long QT syndrome.

Background And Aims: Long QT syndrome (LQTS) and coronary artery disease (CAD) are both associated with increased risk of ventricular tachyarrhythmia However, there are limited data on the incremental risk conferred by CAD in adult patients with congenital LQTS. We aimed to investigate the risk associated with CAD and life threatening events (LTEs) in patients with LQTS after age 40 years.

Methods: The risk of LTEs (comprising aborted cardiac arrest, sudden cardiac death, or appropriate defibrillator shock) from age 40 through 75 years was examined in 1,020 subjects from the Rochester LQTS registry, categorized to CAD ( = 137) or no-CAD ( = 883) subgroups.

Development and Evaluation of a Semi-Nested PCR Method Based on the Gene for the Detection of Infections in Goats.

We developed and evaluated a semi-nested PCR assay for the detection of infection in goats based on the sequence of the gene. Following in silico screening, the specificity of the primers was assessed using reference DNA samples, including , , , , , , , and . To determine the sensitivity of the method, blood infected with 2% parasitemia of was diluted to 10-fold serial dilutions.

The effect of climate crisis on bipolar disorder: A qualitative study about experiences of individuals diagnosed with bipolar disorder.

Introduction: It can be said that the bipolar disorder is influenced by weather events. It is stated that climate change can have direct and indirect effects on bipolar disorder. Determining the impact of the climate crisis on individuals with bipolar disorder may assist in the development of preventive, protective and active treatment interventions for this group.

Polarization-Doped InGaN LEDs and Laser Diodes for Broad Temperature Range Operation.

This work reports on the possibility of sustaining a stable operation of polarization-doped InGaN light emitters over a particularly broad temperature range. We obtained efficient emission from InGaN light-emitting diodes between 20 K and 295 K and from laser diodes between 77 K and 295 K under continuous wave operation. The main part of the p-type layers was fabricated from composition-graded AlGaN.

Difficulties in emotion regulation and attachment styles among Kurdish individuals in Eastern Turkey with substances use disorders.

The aim of this study was to investigate the relationship between attachment style and emotion dysregulation in Kurdish individuals with substance use disorders (SUDs) in Eastern Turkey, a non-Western, Islamic society, in a descriptive cross-sectional design. This study was conducted with 216 individuals with SUDs who were treated at the SBU Van Training and Research Hospital Alcohol and Substance Addiction Treatment Center in Eastern Turkey between April 2023 and June 2023. Almost half of the participants (44.

Sheep Displayed No Clinical and Parasitological Signs upon Experimental Infection with .

Our survey in the Mediterranean region of Türkiye revealed high prevalence of in goats, while no molecular evidence of the parasite was found in sheep grazing in the same pasture. We hypothesized that the parasite may not be infectious to sheep. To test this hypothesis, the present study was designed to evaluate the susceptibility of Akkaraman sheep breed to infection.

Relationships Among Internalized Stigma, Readiness to Change and Treatment Eagerness, and Recovery Among Individuals With Substance Use Disorder in Turkey.

Purpose: To investigate relationships among internalized stigma, readiness to change and treatment eagerness, and recovery among people with substance use disorder (SUD) ( = 131).

Method: This study used a cross-sectional and correlational research design. Multiple linear regression was used for analysis.

Role of larvae in transstadial transmission and endemicity of in chronically infected sheep.

, transmitted by ticks, is the causative agent of ovine babesiosis, a disease characterized by fever, anemia, hemoglobinuria, and high mortality in sheep. This study investigates whether sheep that survived babesiosis without treatment can serve as a source of infection for -free host-seeking larvae in a later season. Three donor sheep were experimentally infected with , and after six months, persistence of was assessed through blood and tick transmission experiments.

Three separate pathways in maintain phosphatidylcholine biosynthesis, which is required for symbiotic nitrogen fixation with clover.

Unlabelled: Phosphatidylcholine (PC) is critical for the nitrogen-fixing symbiosis between rhizobia and legumes. We characterized three PC biosynthesis pathways in and evaluated their impact on nitrogen fixation in clover nodules. In the presence of choline, a PC synthase catalyzes the condensation of cytidine diphosphate-diacylglycerol with choline to produce PC.

Incompetence of Vector Capacity of to Transmit following Feeding on Clinically Infected Goat with High Level of Parasitemia.

A recent molecular survey revealed a high prevalence of in indigenous goats from the Mediterranean region of Türkiye, coinciding with heavy infestations. This geographical overlap has raised the possibility that may serve as a vector for the parasite. To evaluate the potential of to serve as a vector for the parasite, an experimental study was conducted in indigenous goats.

[Awareness and Expectations of Primary Care Clinicians in Chronic Heart Failure Management].

Objective: Chronic heart failure (CHF) management requires a multidisciplinary approach, and it's very important for primary care physicians (PCC) to cooperate with cardiology physicians in this process. In this study, we tried to reveal the awareness and expectations of PCC about CHF management.

Methods: The study was designed as a descriptive survey in a single region and included 549 PCC.