Adverse effects associated with influenza vaccination in patients with COPD: a randomized controlled study.

Objective: The aim of this study was to assess the frequency and type of adverse reactions following influenza vaccination and its effects on lung function, dyspnoeic symptoms, exercise capacity, and clinical acute respiratory illness (ARI) in patients with COPD, and the relationship of these adverse effects to the degree of airflow obstruction.

Methodology: A stratified, randomized, double-blind placebo-controlled study was conducted over an 18-month period at a single university hospital. In total, 125 patients with COPD were randomized to the vaccine group (62 patients who received purified trivalent split-virus vaccine injections) or the placebo group (63 patients).

Respiratory symptoms and pulmonary function of traffic policemen in Thonburi.

A cross-sectional study was conducted to assess whether traffic policemen working in Thonburi district of Bangkok had poorer respiratory health than the normal Thai population. The benefits of wearing masks as a preventative measure against the respiratory hazards of air pollution were assessed. Traffic policemen (n = 629) who had worked in Thonburi and male subjects (n = 303, the control group) were evaluated for respiratory symptoms using the British Medical Research Council questionnaire.