Differentiating flare and infection in febrile lupus patients: Derivation and validation of a calculator for resource constrained settings.

: Patients with Systemic Lupus Erythematous (SLE) are at an increased risk of infection and it is often difficult to differentiate between infection and disease activity in a febrile patient with SLE. : Patients with SLE (SLICC criteria) presenting with fever between December 2018 and August 2021 were included. Neutrophil to lymphocyte ratio (NLR), NEUT-x, -y, -z indices, Erythrocyte sedimentation rate (ESR), C-reactive protein(CRP), C3, C4, anti-dsDNA antibodies, and procalcitonin(PCT) were tested in addition to investigations as per the treating physician's discretion.

Principles of geriatric pharmacology.

Elderly patients are affected by multiple chronic age-related diseases. In prescribing drugs for them one should have sound knowledge of the physiological changes and social issues. Altered drug behaviour in the elderly is to be taken into account.