Publications by authors named "Akshay Bhandari"

Article Synopsis
  • Single-port (SP) robotic surgery is being compared to multi-port (MP) surgery to assess their effectiveness in robotic radical nephrectomy (RN), focusing on various outcomes like surgery time and recovery.* -
  • In a study of 341 patients, the SP group (14% of the total) had smaller tumors and longer operative times compared to the MP group but similar overall safety and recovery metrics.* -
  • SP robotic surgery may lead to shorter hospital stays and smaller incisions, despite longer surgery times, illustrating its potential benefits while maintaining safety comparable to MP methods.*
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Article Synopsis
  • The study compares the safety and feasibility of single-port (SP) robotic partial nephrectomy (RPN) to multiport (MP) RPN in patients, as previous evidence on this topic is limited.
  • Data from 286 patients undergoing retroperitoneal RPN between 2017 and 2023 revealed significant differences in ischemia time, with the MP group having shorter times (16 vs. 22 minutes).
  • The findings suggest that while SP RPN shows longer ischemia times, both approaches yield comparable perioperative and postoperative outcomes, indicating SP RPN is a safe option but needs further investigation for potential benefits and long-term results.
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  • Localized cystic kidney disease (LCKD) is a specific kidney disorder marked by cysts in certain kidney areas, demonstrated in a case of a 41-year-old man with urinary symptoms and hematuria.
  • Initial diagnosis revealed a urinary tract infection, but follow-up imaging showed a concerning 2.6 cm cystic lesion in the right kidney, leading to surgical intervention.
  • The report highlights LCKD's benign nature, differences from progressive renal diseases, various symptoms, diagnostic methods, and similarities in tissue findings with conditions like polycystic kidney disease.
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  • Prostate cancer is a common disease, and outpatient robotic-assisted laparoscopic radical prostatectomy (RALP) is becoming popular due to lower costs and fewer complications, but few studies have focused on patients undergoing pelvic lymph node dissections (PLND) during outpatient procedures.
  • A total of 58,527 RALP surgeries were analyzed from 2016 to 2021, revealing only 3.7% were done outpatient; those without PLND had a higher prevalence of hypertension and postoperative infections compared to those with PLND, but overall complications and readmission rates were similar.
  • The study concluded that while outpatient RALP patients without PLND had more baseline health issues and infections, there were no significant differences in post-surgery
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Retroperitoneal masses present a diagnostic challenge due to their elusive origin and varied clinical manifestations. Among these masses, retroperitoneal liposarcomas, rare tumors of mesenchymal origin, often grow asymptomatically until compressing surrounding structures, necessitating accurate and early diagnosis. Renal angiomyolipomas (AMLs) have also been reported to mimic retroperitoneal liposarcomas on radiographic imaging, further complicating diagnostic processes.

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We aim to compare transperitoneal (TP) and retroperitoneal (RP) robotic partial nephrectomy (RPN) in obese patients. Obesity and RP fat can complicate RPN, especially in the RP approach where working space is limited. Using a multi-institutional database, we analyzed 468 obese patients undergoing RPN for a renal mass (86 [18.

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Introduction: Highly complex renal masses pose a challenge to urologic surgeons' ability to perform robotic partial nephrectomy (RPN). Given the increased utilization of the robotic approach for small renal masses, we sought to characterize the outcomes and determine the safety and feasibility of RPN for complex renal masses from our large multi-institutional cohort.

Methods: We performed a retrospective analysis of patients with R.

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We aim to describe the perioperative and oncological outcomes for salvage robotic partial nephrectomy (sRPN) and salvage robotic radical nephrectomy (sRRN). Using a prospectively maintained multi-institutional database, we compared baseline clinical characteristics and perioperative and postoperative outcomes, including pathological stage, tumor histology, operative time, ischemia time, estimated blood loss (EBL), length of stay (LOS), postoperative complication rate, recurrence rate, and mortality. We identified a total of 58 patients who had undergone robotic salvage surgery for a recurrent renal mass, of which 22 (38%) had sRRN and 36 (62%) had sRPN.

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Objective: To describe the most recent surgical, functional, and oncological outcomes of RPN utilizing one of the largest, prospectively maintained, multi-institution consortium of patients undergoing robotic renal surgery.

Materials And Methods: Data was obtained from a prospectively maintained multi-institutional database of patients who underwent RPN for clinically localized kidney cancer between 2018 and 2022 by 9 high-volume surgeons. Demographic and tumor characteristics as well as operative, functional, and oncological outcomes were queried.

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Introduction: Retroperitoneal robotic partial nephrectomy (RPN) has been shown to have comparable outcomes to the transperitoneal approach for renal tumors. However, this may not be true for completely endophytic tumors as they pose significant challenges in RPN with increased complication rates. Hence, we sought to compare the safety and feasibility of retroperitoneal RPN to transperitoneal RPN for completely endophytic tumors.

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Single-port (SP) robotic surgery is a new technology and early in its adoption curve. The goal of this study is to compare the perioperative outcomes of SP to multi-port (MP) robotic technology for partial nephrectomy. This is a prospective cohort study of patients who have undergone robot-assisted partial nephrectomy using SP and MP technology.

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Article Synopsis
  • Opioid dependency has been a significant problem in the U.S. for the last 20 years, prompting efforts to limit opioid prescriptions.
  • A study analyzed at-home opioid requirements among 65 patients after robotic prostate surgery, revealing that many patients either used no opioids or only a few pills.
  • Key factors influencing opioid use included younger age, lower education levels, and living with family; overall, most patients did not need opioids post-surgery, indicating overprescription issues in the region.
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In recent years, research has questioned the theorized renal-protective value of mannitol infusion during partial nephrectomy. This study considers whether the cessation of routine mannitol administration has shown any benefit or detriment to patients in the contemporary era. We retrospectively reviewed a multi-institution database for an association between mannitol administration and subsequent renal function during follow-up.

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Background: Multiparametric (mp) magnetic resonance imaging (MRI)-ultrasound fusion-targeted biopsy (TB) has improved the detection of clinically significant prostate cancer (csCaP) using the Prostate Imaging Reporting and Data System (PI-RADS) reporting system, leading some authors to conclude that TB can replace the 12-core systematic biopsy (SB). We compared the diagnostic performance of TB with SB at our institution.

Methods: Eighty-three men with elevated prostate-specific antigen levels (6.

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Article Synopsis
  • Most robot-assisted laparoscopic prostatectomies are done with patients in lithotomy position, which can lead to complications, while newer robots allow for a supine position that may reduce these risks.
  • A survey of 92 surgeons showed that although over half considered using supine positioning, only 30% regularly did so, with a preference for lithotomy largely due to team familiarity.
  • The study highlights the need to address training and team dynamics to facilitate safer surgical practices involving supine positioning.
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Background: The aim of this study was to evaluate the association between tumor complexity based on RENAL nephrometry score and complications.

Methods: We retrospectively identified 2555 patients who underwent RPN for renal cell carcinoma. Major complication was defined as Clavien Grade ≥3.

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Background: The role of race on functional outcomes after robotic partial nephrectomy (RPN) is still a matter of debate. We aimed to evaluate the clinical and pathologic characteristics of African American (AA) and Caucasian patients who underwent RPN and analyzed the association between race and functional outcomes.

Methods: Data was obtained from a multi-institutional database of patients who underwent RPN in 6 institutions in the USA.

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To determine the effect of positive surgical margins (PSMs) on oncologic outcomes following robot-assisted partial nephrectomy (RAPN) and to identify factors that increase the likelihood of adverse oncologic outcomes. A multi-institutional database of patients who underwent RAPN with complete follow-up data was used to compare recurrence-free survival (RFS) and overall survival (OS) between 42 (5.1%) patients with a PSM and 797 (94.

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Objective: To analyse whether selective arterial clamping (SAC) and off-clamp (OC) techniques during robot-assisted partial nephrectomy (RPN) are associated with a renal functional benefit in patients with Stage 3-5 chronic kidney disease (CKD).

Patients And Methods: The change in estimated glomerular filtration rate (eGFR) over time was compared between 462 patients with baseline CKD 3-5 that underwent RPN with main arterial clamping (MAC) (n = 375, 81.2%), SAC (n = 48, 10.

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Hilar tumors pose unique challenges during partial nephrectomy. We present the characteristics and outcomes of 263 patients with hilar tumors undergoing robot-assisted partial nephrectomy (RPN) in the largest series to date. Perioperative, pathologic, functional, and oncological outcomes were compared between 1467 (84.

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Introduction: We investigated barriers to the receipt of neoadjuvant chemotherapy by patients undergoing radical cystectomy.

Methods: After institutional review board approval we performed a retrospective chart review from January 1, 2012 to March 1, 2018 of cases of radical cystectomy with urinary diversion for bladder cancer. Patients were placed in 1 of 3 groups according to eligibility to receive neoadjuvant chemotherapy before undergoing cystectomy, as "NAC" if they received neoadjuvant chemotherapy, "No NAC - Declined" if they were eligible but declined neoadjuvant chemotherapy and "No NAC - Ineligible" if they were clinically ineligible to receive neoadjuvant chemotherapy.

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To evaluate the feasibility of postoperative day 1 (POD1) discharge after robotic partial nephrectomy (RPN) and to determine whether a protocol targeting a shorter length of stay (LOS) is associated with any difference in the rate of postoperative complications. We reviewed a prospectively maintained, multi-institutional database of patients who underwent RPN from September 2013 to September 2016. Three of the six participating surgeons used a protocol that targeted discharge on POD1, whereas three surgeons did not.

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Following partial nephrectomy (PN), it is important to prevent any deterioration in estimated glomerular filtration rate (eGFR). At present there are no evidence-based recommendations on when a nephrology consultation should be requested and how to adjust postoperative management when the risk of renal function decline is high. In an effort to address this void, we used our previously published nomogram to define risk groups for a significant decline in eGFR at 3-15 mo after PN.

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Objective: To determine the safety and efficacy of performing partial nephrectomy (PN) on patients with high nephrometry score tumors.

Patients And Methods: We used a prospectively maintained multi-institutional kidney cancer database to identify 144 patients with R.E.

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