Colon targeted dosage form of Capecitabine using folic acid anchored modified carbon nanotube: cytotoxicity, apoptosis and roentgenographic study.

Objective: Development of dosage form comprising of Capecitabine loaded carbon nanotubes for its targeted delivery to the colon.

Method: Single walled carbon nanotubes (SWCNT) were functionalized by -COOH and Chitosan along with Folic acid. Capecitabine was loaded in these SWCNT's, and the system was analyzed by FTIR, SEM and Raman spectroscopy.