Publications by authors named "Akriti Bhattarai"

Pathogen perception generates the activation of signal transduction cascades to host defense. White pine blister rust (WPBR) is caused by J.C.

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Whitebark pine (WBP, Pinus albicaulis) is a white pine of subalpine regions in the Western contiguous United States and Canada. WBP has become critically threatened throughout a significant part of its natural range due to mortality from the introduced fungal pathogen white pine blister rust (WPBR, Cronartium ribicola) and additional threats from mountain pine beetle (Dendroctonus ponderosae), wildfire, and maladaptation due to changing climate. Vast acreages of WBP have suffered nearly complete mortality.

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Article Synopsis
  • Whitebark pine (WBP) is under threat from disease like white pine blister rust, pests, wildfires, and climate change, leading to severe mortality across its range in the Western US and Canada.
  • Genomic technologies have been utilized to effectively identify disease-resistant and climate-adapted seed sources for restoring WBP, including advanced sequencing techniques that produced a detailed genome assembly.
  • The study identified a significant number of candidate genes for disease resistance, particularly focusing on nucleotide-binding leucine-rich-repeat receptors (NLRs), enhancing the ability to understand and improve WBP’s resilience compared to earlier methods.
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Premise: Robust standards to evaluate quality and completeness are lacking in eukaryotic structural genome annotation, as genome annotation software is developed using model organisms and typically lacks benchmarking to comprehensively evaluate the quality and accuracy of the final predictions. The annotation of plant genomes is particularly challenging due to their large sizes, abundant transposable elements, and variable ploidies. This study investigates the impact of genome quality, complexity, sequence read input, and method on protein-coding gene predictions.

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