Obese subjects have significantly higher serum prooxidantantioxidant balance values compared to normal-weight subjects.

Background: It has been reported that obesity is associated with higher levels of oxidative stress. We aimed to evaluate the hypothesis that pro-oxidant antioxidant balance (PAB) values could be affected by adiposity and to assess the association between PAB levels and indices of obesity.

Methods: Subjects (n = 733) were recruited and tlen were divided into 3 groups of normal-weight (BMI < 25, n = 207), overweight (25 < BMI < 30, n = 375), and obese (BMI > 30, n = 151).

Association between C-reactive protein, pro-oxidant-antioxidant balance and traditional cardiovascular risk factors in an Iranian population.

Background: Inflammatory states are known to cause an imbalance in the redox status. We aimed to study the possible associations between pro-oxidant-antioxidant balance (PAB) and serum high-sensitive C-reactive protein (hs-CRP) concentrations and traditional cardiovascular disease (CVD) risk factors in an unselected Iranian population and in groups of individuals with specific disease.

Methods: The study was conducted among an unselected population of 758 male subjects.