Dysregulation of Autophagy Occurs During Congenital Cataract Development in βA3ΔG91 Mice.

Purpose: To examine lens phenotypic characteristics in βA3ΔG91 mice and determine if βA3ΔG91 affects autophagy in the lens.

Methods: We generated a βA3ΔG91 mouse model using CRISPR/Cas9 methodology. Comparative phenotypic and biochemical characterizations of lenses from postnatal day 0 (P0), P15, and 1-month-old βA3ΔG91 and wild-type (WT) mice were performed.

Ocular Complications after COVID-19 Vaccination, Vaccine Adverse Event Reporting System.

In December 2020, the U.S. Food and Drug Administration licensed COVID-19 vaccines for emergency use authorization.