Publications by authors named "Akos Janos Varga"
Int J Mol Sci
November 2023
Article Synopsis
- Micro-environmental factors like stromal and immune cells, along with hormones, significantly influence the progression of melanoma.
- A study with 89 melanoma patients revealed a notable link between elevated gastrin levels and increased melanoma thickness and metastasis, suggesting higher cancer progression risks.
- Gastrin was shown to promote melanoma cell migration and invasion through CCK2 receptors, with interactions in the tumor environment potentially exacerbating these effects, especially when combined with dermal fibroblasts/myofibroblasts.
