Publications by authors named "Akos Botos"

Case-report: Rosai-Dorfman disease, also known as sinus histiocytosis with massive lymphadenopathy is a rare, benign non-Langerhans cell histiocytosis, that typically involves the lymph nodes, but may also involve extranodal sites. We present a 58- years- old female patient who complained of a palpable mass in her left breast surrounded by 15-20 livid cutaneous lesions, resembling malignant breast cancer with cutaneous metastasis. Despite of core biopsy of the tumor and excisional biopsy one of the lesions, correct diagnosis of RDD was achieved only by complete pathological examination of the whole lesion after surgical excision.

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Catalysis of chemical reactions by nanosized clusters of transition metals holds the key to the provision of sustainable energy and materials. However, the atomistic behaviour of nanocatalysts still remains largely unknown due to uncertainties associated with the highly labile metal nanoclusters changing their structure during the reaction. In this study, we reveal and explore reactions of nm-sized clusters of 14 technologically important metals in carbon nano test tubes using time-series imaging by atomically-resolved transmission electron microscopy (TEM), employing the electron beam simultaneously as an imaging tool and stimulus of the reactions.

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In organic synthesis, the composition and structure of products are predetermined by the reaction conditions; however, the synthesis of well-defined inorganic nanostructures often presents a significant challenge yielding nonstoichiometric or polymorphic products. In this study, confinement in the nanoscale cavities of single-walled carbon nanotubes (SWNTs) provides a new approach for multistep inorganic synthesis where sequential chemical transformations take place within the same nanotube. In the first step, SWNTs donate electrons to reactant iodine molecules (I2), transforming them to iodide anions (I(-)).

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Background/aims: Surgical technique and experience are considered as significant determinants of the successful treatment of recto-sigmoid malignancies.

Methods: Two hundred patients operated on between 2005 and 2009 were prospectively followed with an average of 39.8 months.

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Background: Our aim was to investigate the presence of free cancer cells found in lavage cytology specimens taken from the proximity of tumors during the course of curative open and laparoscopic colorectal resections and then examine and compare the long-term disease outcomes in cases of negative and positive cytology. Based on the results, we were hoping to identify the place of peritumoral lavage cytology among prognostic factors for disease recurrence.

Methods: Between January 1, 2005 and December 31, 2007 intraoperative peritoneal lavage cytology was performed in 145 patients who underwent curative colorectal procedures.

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Mucocele is a mucin-filled cavity, which can be multi-loculated as well. Mucocele is relatively rarely found in the appendix. The disease does not cause any symptoms in most cases, and it is usually an accidental finding.

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The widespread use of tension free surgical techniques and the modern, tissue-friendly surgical meshes have led to the development of new surgical techniques. The increasing importance of minimal invasive surgery became apparent in abdominal wall reconstructions, too, and their use has been justified by literature data. This procedure combines the advantages of minimal invasive surgery with tension free technique.

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It is widely accepted today, that laparoscopic exploration of the common bile duct is an effective method for the treatment of obstructive jaundice, when it is caused by ductal calculi. In case of periampullary lesions, endoscopic stenting or surgical biliodigestive diversion might be the treatment of choice when radical solution is impossible or not necessary. The latter is still performed by laparotomy in a large number of cases due to technical challenges of the biliodigestive anastomosis in the laparoscopic approach.

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Relaxation of the pelvic floor causes changes in the anatomy. This results in symptoms, which can be treated with different operations. The use of modern, minimal invasive methods and tension free mesh implants for the reconstruction is widely used in rectocele repair as well.

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The use of laparoscopy in colorectal surgery is expanding. Minimally invasive surgery of benign lesions is widely accepted and can be performed with good results even during the learning curve. After gaining adequate expertise one can remove polyps which can not be treated with a colonoscope and early colonic carcinomas.

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Since the first laparoscopic common bile duct exploration in Hungary published in 1999 the authors use the technique themselves. We review and analyse our activity between 1 June 1999 and 31 August 2003. The minimally invasive approach was selected in twelve patients with obstructive jaundice for suspected bile duct stones.

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In recent years in Hungary similarly to the worldwide trend the treatment of inguinal hernias has changed. New tension-free methods were developed and--after the introduction by the Department of Surgery, Medical Faculty, University of Pécs--Lichtenstein's method is widely used. Lichtenstein's method has become the gold standard at our department because of its highly favourable results: simple technique, minimal postoperative pain, recurrence rate below 1%, short hospital stay, very low complication rate and early return to physical activity.

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Today's development in breast cancer surgery are characterized by the principle of the smallest necessary intervention in contrast with the radicality of the past. To achieve this goal the primary and crucial task is the recognition of early (stage I or II) breast cancer. The National Screening Program started 2002 provides ideal conditions.

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The "Endomedix Laparoscan" and the "Leopard" and "Panther" intraoperative ultrasounds were successfully used for the detection of unsuspected common bile duct stones during laparoscopic cholecystectomy (LC). Out of 60 patients six had common bile duct (CBD) stones and in one patient sludge has been seen. In patients with CBD stones, four small calculi have been observed in one patient, despite negative intraoperative cholangiography (IC).

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