Publications by authors named "Akopova A"

The article provides a case of primary diagnosis of IgG4-related disease in a patient with Burkitt lymphoma.

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The article describes clinical observations of helminthiasis detection in 18 of 208 patients during video capsule endoscopy (VCE). Indications for the appointment of VCE were complex clinical situations associated with the search for inflammatory diseases of the small intestine and sources of small intestine bleeding. Because of the high cost of VCE the diagnosis of parasitic diseases should be based on laboratory techniques in clinical practice.

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Aim: To clarify the indications for capsular endoscopy (CE) in patients with celiac disease.

Materials And Methods: The study included 10 patients with celiac disease (6 women, 4 men) aged 22 to 69 years. The median age was 42.

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Aim: To estimate the value of video capsule endoscopy (VCE) in the diagnosis of small intestine (SI) diseases..

Subjects And Methods: A total of 134 patients, including 72 (53.

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The article describes the diffuse esophageal spasm which is not amenable to conservative treatment.

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The clinical case of chronic post-hemorrhagic iron deficiency anemia in patients with large hiatal hernia is represented in this article.

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Maturity-onset diabetes of the young (MODY) is a clinically heterogenic group of diseases, with an autosomal dominant mode of inheritance and gene mutations resulting in dysfunction of pancreatic β cells. The type of diabetes and further treatment policy can be reliably determined on the basis of the data of a molecular genetic study that confirms gene mutations. Today there are known mutations of 8 genes, of which glucokinase (GCK) gene mutation that leads to the development of MODY2 and occurs most frequently.

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The results of an investigation of radiation environment on board the ISS with apogee/perigee of 420/380 km and inclination 51.6 degrees are presented. For measurement of important characteristics of cosmic rays (particles fluxes, LET spectrum, equivalent doses and heavy ions with Z > or = 2) a nuclear photographic emulsion as a controllable threshold detector was used.

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The results of investigations of the neutron component (E=1-10 MeV) of cosmic radiation on board the "Armenian Airlines" aircrafts using nuclear photoemulsion are presented. The emulsions were exposed on the flights from Yerevan to Moscow, St.-Petersburg, Beirut, Athens, Frankfurt, Amsterdam, Paris and Sofia, and on Concord supersonic flights from Paris to New York.

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We propose to study the radiation environment on board different flight vehicles: cosmos-type satellites, orbital stations, Space Shuttles and civil (sonic and supersonic) aircraft. These investigations will be carried out with single type of passive detector, namely, nuclear photoemulsions (NPE) with adjustable threshold of particle detection within broad range of linear energy transfer (LET) that is done by means of the technique of selective development of NPE exposed in space. These investigations will allow, one to determine: integral spectra of LET of charged particles of cosmic ray (CR) over a wide range from 2.

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The results of probing the radiation environment on board different civil aviation planes with single-type detectors (nuclear emulsions), with particular emphasis to the cosmic radiation flux measured in-side aircraft, are presented. The measurement results make it possible to find the absorbed and equivalent doses induced by the cosmic radiation neutrons and charged particles.

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A joint NASA-Russian study of the radiation environment inside a SPACEHAB 2 locker on Space Shuttle flight STS-57 was conducted. The Shuttle flew in a nearly circular orbit of 28.5 degrees inclination and 462 km altitude.

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Joint Soviet-American measurements of the neutron component of space radiation (SR) were carried out during the flight of the Soviet biosatellite Cosmos-2044. Neutron flux densities and differential energy spectra were measured inside and on the external surface of the spacecraft. Three energy intervals were employed: thermal (En < or = 0.

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Integral linear energy transfer (LET) spectra of cosmic radiation (CR) particles were measured on five Cosmos series spacecraft in low Earth orbit (LEO). Particular emphasis is placed on results of the Cosmos 1887 biosatellite which carried a set of joint U.S.

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Two methods for measuring neutrons in the range from thermal energies to dozens of MeV were used. In the first method, alpha-particles emitted from the 6Li(n,alpha)T reaction are detected with the help of plastic nuclear track detectors, yielding results on thermal and resonance neutrons. Also, fission foils are used to detect fast neutrons.

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The most important characteristic of the hazard due to cosmic radiation is the spectrum of linear energy transfer (LET), which enables one to estimate the dose equivalent. This has prompted us to study LET spectra of cosmic radiation aboard Cosmos-1129 using nuclear emulsions as a threshold detector.

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The microflora from the Armenian yoghurt was studied during its growth on the optimal for the medium (skim milk) using objectives of the Peshkoff system. It was shown that certain organisms of Lactobacterium jogorti tended to branch at the early stages of their growth, and the cells elongated and formed complex coils and helices by the third-fourth day of growth. Compact aggregates of cocci having angular outlines appeared in the culture of Streptococcus thermophilus by the end of the second day of growth.

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The authors examined 250 children suffering from various acute gastrointestinal diseases, and 100 healthy children. Positive cultures of bacteria belonging to the Citrobacter genus were obtained in 38% of the patients and in 20% of the healthy persons. There were revealed no cultural or biochemical differences between the strains isolated from the sick and healthy individuals.

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Changes in the cell wall and various stages of lysis become manifested on the 1-2 day of development of the yogort bacteria. Heteromorphous individuals appear both in the culture of streptococci and rods. The nuclear apparatus of the yogort bacteria is exteremely polymorphous whereas in the streptococci it undergoes changes from compact nucleoids which are either round or crescent shaped or take the form of massive super-nuclei in heteromorphous individuals.

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