[Effects of total lavage of the gastrointestinal tract on the regulatory mechanisms of water-electrolyte metabolism in patients who had undergone colon surgery].

The main parameters of homeostasis in total lavage of the gastrointestinal tract with isotonic solution (osmolality of 290 mosm/l) were studied in 85 patients. It was revealed that lavage facilitates increase of the volume of circulating blood by more than 10%. Prolonged (over 6 hours) operative intervention and severe blood loss (20% of the circulating volume) which call for the conduction of infusion-transfusion therapy during lavage lead to considerable water loading of the patient's organism.

[The role of disorders of mineralocorticoid function of the adrenal glands in the development of infertility in patients with left-side varicocele].

A combined study, including phlebography, phlebotonometry, orchidometry, morphometric determination of microcirculatory testicular volume, microscopic and biochemical ejaculate studies, determination of peripheral blood levels of adrenocortical mineral glucocorticoid hormones before and after ACTH administration in the blood, sampled from various veins prior to phlebography, assessment of osmolality, pO2 and pCO2 in the blood samples from spermatic venous plexus, left renal vein and intrarenal portion of the vena cava inferior, and determination of plasma renin activity in renal veins, was conducted in 55 patients with varicocele. A considerable increase in orthostatic blood pressure of the left spermatic venous plexus is demonstrated that may be due to retrograde blood flow in the left testicular venous plexus, resulting in a microcirculatory disturbance and gradual atrophy of a testicle. There was a correlation between the severity of varicocele and left-testicular volume which was absent for total testicular volume, while microcirculatory volumes of the testes differed significantly, suggesting the absence of hemodynamic disorders in the contralateral testicle and, consequently, no spermatogenetic impairment due to hemodynamic changes in cases of a unilateral varicocele.

[The cytological characteristics of Malherbe's necrotizing epithelioma].

Histocytological examinations of 12 cases of Malherbe's tumor have made it possible to define the criteria of the cytologic diagnosis of this tumor and to distinguish the signs that permit its differentiation from related diseases.

[Cyclic nucleotides and serotonin in the blood of patients with functional and inflammatory diseases of the large intestine].

The blood levels of cyclic nucleotides and serotonin were measured in 143 patients with functional and inflammatory diseases of the large intestine. The patients were divided into 3 groups administered various treatment: drug (basic) therapy in Group 1, basic therapy + alternating magnetic field in Group 2, and basic therapy + sinusoidal modulated currents in Group 3. Follow-up of the examined parameters over the course of treatment has shown that by day 16 of inpatient treatment they normalize, this demonstrating the treatment efficacy.

[Cytomorphology of fasciitis and its differential diagnosis].

Cytohistologic correlations were studied in 15 cases of fasciitis (nodular--10 and proliferative--5). Cytologic examination of punctate obtained from tumor-like lesions of the soft tissue is the only morphologic procedure available for pretreatment diagnosis of fasciitis. It assured a reliable diagnosis in 9 out of 15 cases.

[Characteristics of cerebral blood flow in children with cerebral palsy during the dynamics of treatment].

Using methods of circulatory radioencephalography and encephaloscintigraphy the authors identified changes in the parameters of the cerebral blood flow (CBF) in 103 patients with childhood cerebral paralysis. Depending on predominant disorders of the CBF in the microcirculatory, arterial or venous systems, vasoactive drugs administered for hemodynamic correction were used differentially.

[Dopamine modification of the Ca-component of the action potential in the neuron soma of the mollusk L. stagnalis].

Dopamine has been found to decrease reversibly the action potential rising phase in identified L. stagnalis neurones. Using voltage-clamp and intracellular dialysis techniques it is shown that dopamine inhibits electroexcitable Ca-current, and changes in Ca-current determine those in the action potential shape.

[Brain monoamine oxidase in craniocerebral trauma].

Effect of craniocerebral trauma on monoamine oxidase (MAO) activity was studied. The activity of MAO with monoamines as substrates was shown to decrease. In this case transformation of MAO properties was observed: the enzyme exhibited an ability to deaminate di- and polyamines.

[Concentration and distribution of glycogen in the brain following experimental cranio-cerebral injuries].

The amount and distribution of glycogen in the brain tissue in closed craniocerebral injury were studied by electron microscopy. It is shown that 24 hours after the injury the number of glycogen granules in different areas of the brain, and especially in its stem, increases sharply. The glycogen granules are found in the cytoplasm of the neurones and their processes, in the synapses, and in the cytoplasm of the glial cells.