Publications by authors named "Akkuzu G"

Objectives: Familial Mediterranean Fever (FMF) is a hereditary autoinflammatory disease affecting both genders in reproductive age. In this study, we aimed to investigate the relation between FMF and pregnancy on both maternal and fetal aspects.

Material And Methods: In this retrospective, single-center, descriptive study we analysed total of 95 pregnancies of 40 FMF patients.

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  • If a person has a small lesion (growth) in their body that's less than 3 cm and they don't have any symptoms, it's usually okay to just keep an eye on it.
  • Many times, these small lesions don’t cause any problems and can heal on their own.
  • So, doctors often recommend watching the lesion to see if it changes instead of doing surgery right away.
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Objectives: Recurrent monoarthritis (RM) is a major challenge of many rheumatic diseases. Ablation is a well-known technique in the treatment of benign or malign lesions of different etiologies. We aimed to to investigate the success and safety of microwave ablation (MWA) as an adjunctive therapy in a cohort of medical treatment-resistant RM.

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  • The condition known as pseudo-pseudo Meigs' syndrome (PPMS) occurs in systemic lupus erythematosus (SLE) patients and is characterized by ascites, pleural effusion, and elevated CA-125 levels without any ovarian cancer.
  • A 33-year-old female patient was diagnosed with SLE after experiencing persistent pleural effusion and new onset massive ascites alongside increased CA-125 levels, which led to a renal biopsy revealing class-V lupus nephritis.
  • Treatment with immunosuppressants resulted in significant improvement of SLE symptoms and PPMS components, including the ascites and pleural effusion, without the necessity for diuretics, highlighting the importance of thorough evaluation and treatment in such
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Protracted febrile myalgia syndrome (PFMS) is a rare form of familial Mediterranean fever (FMF) characterised by prolonged myalgia. The duration of PFMS is much longer than a typical 2-5-day attack familial Mediterranean fever and lasts for 2-6 weeks until they treated with corticosteroids. Colchicine is not effective for control of PFMS's attacks.

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  • Rheumatoid arthritis (RA) is a long-lasting disease that causes joint pain and problems moving, especially in bigger joints like shoulders.
  • In severe cases, treatments like medications and surgery don’t always work, leading to very limited movement and pain.
  • A new treatment called microwave ablation (MWA) has shown success, helping a patient relieve pain and improve movement without serious risks.
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Objective: Renal biopsy contributes to the diagnosis, follow-up, and treatment of many rheumatic conditions. This study assessed the diagnostic role and safety of renal biopsies in a tertiary rheumatology clinic.

Methods: Renal biopsies performed between June 2020 and December 2022 were screened, and demographic, clinical, histopathological, and safety data were collected from patient records.

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Cardiac involvement (CI) is rare in Behçet syndrome (BS), but the important point is that CI may be the first manifestation of the disease. The presence of CI worsens the prognosis of BS, so early diagnosis and early initiation of immunosuppressive treatment (IST) are vital. Coronary aneurysm may develop spontaneously in these patients, or any vascular intervention may cause aneurysm with a pathergy-like reaction.

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Behcet's syndrome is a variable vessel vasculitis characterized by recurrent oral and genital ulcers with concomitant skin, ocular, neurologic, gastrointestinal, and joint involvement. Herein, we present a patient who was diagnosed with Behcet's syndrome, which with magnetic resonance angiography showed occlusion of the right subclavian artery at the level of the thoracic outlet and reverse flow in the right vertebral artery consistent with subclavian steal syndrome. In addition, partial narrowing was noted in the left renal artery.

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Vasculitis is the inflammatory changes in vessels of any size that usually have a systemic involvement with a quite variable clinical presentation affecting various organs. Although systemic presentation is more common, in some cases localized inflammation of vasculature of a single organ or limited branches of aorta are reported. Here we present, an isolated vasculitis of bilateral inferior thyroidal arteries in a female patient aged 49 years, who presented with neck pain and was diagnosed with ultrasonography and computed tomographic angiography.

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Objective: An increasing number of new on-set autoimmune-inflammatory rheumatic diseases (AIRD) after COVID-19 vaccination has begun to be reported in the literature. In this article, we present our patients with new-onset AIRD after vaccination for COVID-19 and review the literature on the subject.

Patients And Methods: We investigated the clinical characteristics and laboratory parameters of previously described "newly developed AIRD in individuals recently vaccinated for COVID-19", in 22 cases vaccinated with one of the COVID-19 vaccines (BNT162b2 or CoronaVac) approved in our country.

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VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a newly defined disorder in which treatment is still unclear. Herein, a patient with VEXAS syndrome who had atypical findings and an interesting treatment course is presented as a case report. He had fatigue, recurrent fever, pulmonary infiltrates, proteinuria, anemia, leucopenia, transient skin rush and increased acute phase reactants.

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  • Patients with systemic lupus erythematosus (SLE), a disease that affects the immune system, are more likely to get different kinds of infections when they take medicines that weaken their immune system.
  • A 48-year-old woman with SLE had a high fever and low blood cell counts, which doctors initially thought were due to her SLE.
  • After further testing showed she had leishmaniasis, a disease caused by a parasite, she was treated successfully with medicine and got better quickly!
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Relapsing polychondritis (RP) is a a rare multisystemic disease and it affects cartilaginous tissue and proteoglycan rich organs. The spectrum of clinical features are intermittent inflammation involving especially the auricular and nasal regions. In some patients with RP, systemic vasculitis, autoimmune diseases or malignancy may accompany.

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Palmoplantar pustular psoriasis (PPP) is a rare clinical form of psoriasis. It is usually seen on the palms and soles, and affects patients' quality of life. In most cases, topical or systemic treatments are not sufficiently effective, so management of PPP is generally difficult.

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To define the learning needs of patients with gynecological oncology. The study was performed as a descriptive study. A total of 92 patients were participated.

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Background: Functional status is the ability to perform daily activities. Little is known about quality of life and health status of gynaecological cancer patients. The present study therefore aimed to evaluate the functional status of women receiving treatment for gynecological oncological disease while not hospitalised.

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Aim: Studies have shown effects of surgery, radiation and chemotherapy on quality of life in cases of gynaecological cancer. Very few studies are available examining the quality of life of individuals in Turkey who have been diagnosed with gynaecological cancer and undergoing treatment.

Method: This study was performed to evaluate the quality of life of such patients using the EORTC-QLQ-C30 Quality of Life Index.

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Background: This study was planned to determine the knowledge of testicular cancer (TC), risk factors and testicular self-examination (TSE) among university students.

Methods: A survey study was conducted at a university located in Ankara, Turkey with 634 male students.

Results: Almost half of them (44%) heard TC during their education and life but majority of participants has lack of knowledge about sign and symptoms of TC.

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Introduction: We evaluated the opinions and recommendations of patients at moderate to high risk for pressure ulceration and their caregivers about discharge education and asked them to evaluate an educational brochure about pressure ulcer prevention.

Subjects And Setting: The study group comprised 33 hospital patients and 33 caregivers. Approximately half of the subjects (54.

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Conclusions: The results of this preliminary study demonstrate that with regard to determining the efficacy of intratympanic (IT) gentamicin treatment in patients with Meniere's disease, the reliability of testing for vestibular evoked myogenic potentials (VEMPs) is comparable to that of caloric tests. Compared with caloric tests, VEMP measurements are more comfortable and take less time. The results of VEMP and caloric testing do not correlate with the results of hearing tests.

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