[Development of severe aplastic anemia during steroid therapy for autoimmune hemolytic anemia].

A 50-year-old male patient was admitted for close monitoring of anemia (hemoglobin level, 5.0 g/dl). Autoimmune hemolytic anemia (AIHA) of warm type was diagnosed based on the elevated reticulocyte and bone marrow erythroblast counts, elevated indirect bilirubin level, serum haptoglobin level below the detection limit, and positive direct Coombs test result.

Environmental reservoir dynamics predict global infection patterns and population impacts for the fungal disease white-nose syndrome.

Disease outbreaks and pathogen introductions can have significant effects on host populations, and the ability of pathogens to persist in the environment can exacerbate disease impacts by fueling sustained transmission, seasonal epidemics, and repeated spillover events. While theory suggests that the presence of an environmental reservoir increases the risk of host declines and threat of extinction, the influence of reservoir dynamics on transmission and population impacts remains poorly described. Here we show that the extent of the environmental reservoir explains broad patterns of host infection and the severity of disease impacts of a virulent pathogen.

[Acquired hemophilia A accompanied by immune thrombocytopenia].

A 72-year-old man was hospitalized because of thrombocytopenia (0.5×10/µl) and anemia. The bone marrow test result revealed excessive numbers of megakaryocytes and no platelet adhesion.

[Easy screening of outpatients for atrial fibrillation by analyzing fingertip pulse wave variation].

Aim: Atrial fibrillation (AF), which can lead to cardioembolic stroke, is often not properly diagnosed in hospital outpatient departments or medical clinics. We therefore used a pulse analysis to screen patients for AF, and examined the benefits of using this method in screening.

Methods: We performed screening of the hospital's first-visit and ambulatory patients during the afternoon in 2014 (total number, 50,875; true number, 16,356), mainly targeting patients older than 65 years of age.

Systemic and rapidly progressive light-chain deposition disease initially presenting as tubulointerstitial nephritis.

A 42-year-old woman was admitted to a hospital after first-time detection of proteinuria and hematuria during a routine medical check-up. Because her serum creatinine level had rapidly increased from 0.9 to 3.

[Prospects of CyberKnife stereotactic radiation therapy for cerebral vascular malformations and functional diseases].

Minimally invasive stereotactic radiation therapy has become one of the promising options for treating patients with intracranial diseases. Among the currently available instruments, the CyberKnife system (Accuray Inc., Sunnyvale, CA) is a unique apparatus equipped with image-guided target locating system.

Acoustic emission measurement using a strain-insensitive fiber Bragg grating sensor under varying load conditions.

Acoustic emission (AE) during a pressure test of a carbon fiber-reinforced plastic tank was measured using a fiber Bragg grating (FBG) sensor and, for comparison, using a conventional piezoelectric sensor. The FBG-inscribed optical fiber was used not only as an optical transmission line but also as an ultrasonic transmission line. The FBG sensor showed resonant characteristics and could detect AE continuously during the test.