Publications by authors named "Akito Fujisawa"
Article Synopsis
- The aza-Prins reaction of a specific tetrahydroquinoline compound with 1,2-dicarbonyl compounds was successful, yielding tricyclic benzazocines in 20-86% yields under HCl conditions.
- The reaction demonstrated stereoselectivity, particularly favoring the formation of the 2,4- isomer, and when combined with an enantiopure ketoester, produced a mixture of diastereomers.
- These diastereomers were separable, allowing for the creation of enantiopure tricyclic benzazocines and also facilitating the synthesis of spirooxindole derivatives using isatin derivatives.
