Current Trends and Perspectives of Pressure Wire-Based Coronary Artery Bypass Grafting.

Fractional flow reserve (FFR) has been well validated as a modality for evaluating myocardial ischemia, demonstrating the superiority of FFR-guided percutaneous coronary intervention (PCI) over conventional angiography-guided PCI. As a result, the strategy for coronary artery bypass grafting (CABG) is shifting toward FFR guidance. However, the advantage of FFR-guided CABG over angiography-guided CABG remains unclear.

Alcohol septal ablation in drug-refractory hypertrophic obstructive cardiomyopathy patient with multiple comorbidities.

Unlabelled: Septal reduction therapy is an effective treatment for hypertrophic obstructive cardiomyopathy (HOCM). Alcohol septal ablation (ASA) is indicated for HOCM patients who are ineligible for surgical myectomy, but several tips exist for the management of high-risk patients with ASA. Here, we present a case of successful ASA in a HOCM patient with multiple comorbidities, including severe obesity, drug-refractory bronchial asthma, poorly controlled diabetes, and steroid-induced immunosuppression.

Three-dimensional Analysis of the Distribution of Smooth and Skeletal Muscle Tissue Around the Female Urethra.

Introduction And Hypothesis: The urethra is surrounded by layers of smooth muscle, including inner longitudinal and outer circler muscles, as well as the skeletal muscle of the external urethral sphincter. However, the extent of these muscles and their relationship with the levator ani (LA) remain unclear. This study aimed to clarify the composition of muscle layers around the female urethra and their three-dimensional arrangements.

Plasma SVEP1 Levels Predict Cardiovascular Events in Hypertrophic Cardiomyopathy Beyond Conventional Clinical Risk Models Including NT-proBNP.

Background: Hypertrophic cardiomyopathy is the most common genetic cardiomyopathy and causes major adverse cardiovascular events (MACE). SVEP1 (Sushi, von Willebrand factor type A, epidermal growth factor, and pentraxin domain containing 1) is a large extracellular matrix protein that is detectable in the plasma. However, it is unknown whether adding plasma SVEP1 levels to clinical predictors including NT-proBNP (N-terminal pro-B-type natriuretic peptide) improves the prognostication in patients with hypertrophic cardiomyopathy.

Anatomy of the distal tendinous structure of the triceps brachii: implications for the role of the triceps brachii to resist valgus elbow forces during baseball pitching.

Background: Biomechanical studies suggest that the triceps brachii muscle generates resistive force against valgus stress on the elbow during baseball pitching. However, given the parallel fiber orientation in the distal tendinous structure of the triceps brachii, the mechanism behind this anti-valgus force remains unclear. In the present study, we aimed to examine the anatomy of the distal tendinous structure of the triceps brachii using bony morphological, macroscopic, and histological methods.

Does sound symbolism need sound?: The role of articulatory movement in detecting iconicity between sound and meaninga).

Ever since de Saussure [Course in General Lingustics (Columbia University Press, 1916)], theorists of language have assumed that the relation between form and meaning of words is arbitrary. However, recently, a body of empirical research has established that language is embodied and contains iconicity. Sound symbolism, an intrinsic link language users perceive between word sound and properties of referents, is a representative example of iconicity in language and has offered profound insights into theories of language pertaining to language processing, language acquisition, and evolution.

Cervical Spine Range of Motion and Sleep Disturbances in Patients With Atopic Dermatitis: A Cross-Sectional Study.

Background: Sleep disturbances are common and distressing among patients with atopic dermatitis (AD), often resulting in a cycle of worsening skin conditions. Among various factors affecting sleep in AD, cervical spine movement has been suggested to influence sleep quality; however, these studies mostly relied on subjective measures. Owing to the lack of objective and quantitative analyses of cervical spine movement, its association with sleep disturbances remains poorly understood.

Optimal Strategy for Complete Revascularization in ST-Segment Elevation Myocardial Infarction and Multivessel Disease: A Network Meta-Analysis.

Background: In patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease, most but not all randomized trials have reported that complete revascularization (CR) offers advantages over culprit vessel-only revascularization. In addition, the optimal timing and assessment methods for CR remain undetermined.

Objectives: The purpose of this study was to identify the optimal revascularization strategy in patients with STEMI and multivessel disease, using a network meta-analysis of randomized controlled trials.

Ethical Use of Cadaveric Images in Anatomical Textbooks, Atlases, and Journals: A Consensus Response From Authors and Editors.

Nowadays, consent to use donor bodies for medical education and research is obtained from the body donors and their families before the donation. Recently, the International Federation of Associations of Anatomists (IFAA) published guidelines that could restrict the appearance of cadaveric images in commercial anatomical resources such as textbooks and other educational products. These guidelines state that the donor must expressly consent to using such images for this purpose.

Iconicity Emerges From Language Experience: Evidence From Japanese Ideophones and Their English Equivalents.

Iconicity is a relationship of resemblance between the form and meaning of a sign. Compelling evidence from diverse areas of the cognitive sciences suggests that iconicity plays a pivotal role in the processing, memory, learning, and evolution of both spoken and signed language, indicating that iconicity is a general property of language. However, the language-specific aspect of iconicity, illustrated by the fact that the meanings of ideophones in an unfamiliar language are hard to guess (e.

Detection of late gadolinium enhancement in patients with hypertrophic cardiomyopathy using machine learning.

Background: Late gadolinium enhancement (LGE) on cardiac magnetic resonance (CMR) in hypertrophic cardiomyopathy (HCM) typically represents myocardial fibrosis and may lead to fatal ventricular arrhythmias. However, CMR is resource-intensive and sometimes contraindicated. Thus, in patients with HCM, we aimed to detect LGE on CMR by applying machine learning (ML) algorithm to clinical parameters.

Description of a new species of the genus Archaeoglenes Broun, 1893 (Coleoptera, Tenebrionidae, Phrenapatinae) from the Ryukyus, Japan, with ecological insights.

A new species, Archaeoglenes fujikawai sp. nov. (Coleoptera, Tenebrionidae, Phrenapatinae), is described and illustrated from Okinawa-jima and Amami-ôshima Islands in the Ryukyu Archipelago.

Application and evaluation of carbonate apatite granules for mandibular bone defect reconstruction after jawbone cyst enucleation-a retrospective case series.

Purpose: To evaluate the effectiveness of COAp granules in the mandibular bone defects by using computed tomography (CT) images.

Methods: This study was retrospective case series of mandibular bone defect reconstruction using COAp granules. Six patients with jawbone cysts treated by simultaneous grafting COAp granules after cyst enucleation were enrolled.

The improvement of a refractory enterocutaneous fistula with colchicine in a patient with Crohn's disease who had an MEFV gene mutation.

Enterocutaneous fistulas (ECFs) occurring in the setting of Crohn's disease (CD) are difficult to cure with medical treatment alone and affects a patient's quality of life. A 39-year-old man was diagnosed with an ileocolitis-type CD in 2007. His inflammation was insufficiently controlled despite the administration of an anti-tumor necrosis factor-alpha antibody.

Comprehensive Proteomics Profiling Identifies Circulating Biomarkers to Distinguish Hypertrophic Cardiomyopathy From Other Cardiomyopathies With Left Ventricular Hypertrophy.

Background: Distinguishing hypertrophic cardiomyopathy (HCM) from other cardiomyopathies with left ventricular hypertrophy (LVH), such as hypertensive LVH, transthyretin amyloid cardiomyopathy, and aortic stenosis, is sometimes challenging. Using plasma proteomics profiling, we aimed to identify circulating biomarkers and dysregulated signaling pathways specific to HCM.

Methods: In this multicenter case-control study, plasma proteomics profiling was performed in cases with HCM and controls with hypertensive LVH, transthyretin amyloid cardiomyopathy, and aortic stenosis.

Implementation of optically simulated luminescent dosimeter for quality control of gamma ray dose of an accelerator-based neutron source.

Background: Neutron beams utilized for performing BNCT are composed of a mixture of neutrons and gamma rays. Although much of the dose delivered to the cancer cells comes from the high LET particles produced by the boron neutron capture reaction, the dose delivered to the healthy tissues from unwanted gamma rays cannot be ignored. With the increase in the number of accelerators for BNCT, a detector system that is capable of measuring gamma ray dose in a mixed neutron/gamma irradiation field is crucial.

A national survey of medical staffs' required capability and workload for accelerator-based boron neutron capture therapy.

This study aimed to identify the required capabilities and workload of medical staff in accelerator-based boron neutron capture therapy (BNCT). From August to September 2022, a questionnaire related to the capabilities and workload in the accelerator-based BNCT was administered to 12 physicians, 7 medical physicists and 7 radiological technologists engaged in BNCT and 6 other medical physicists who were not engaged in BNCT to compare the results acquired by those engaged in BNCT. Only 6-21% of patients referred for BNCT received it.

In vivo movement interrelationships among the medial meniscus, joint capsule, and semimembranosus during tibial rotation.

The meniscal position within the knee is critical to maintain normal knee function. The joint capsule might dynamically coordinate the medial meniscus (MM) by transmitting a semimembranosus action. However, their interrelationships in vivo are unclear.