Publications by authors named "Akisa Tsunemi"
Hyperammonemia induced by 5-fluorouracil(5-FU)is known as a rare adverse event, but there are few reports of hyperammonemia occurring during FP(5-FU plus CDDP)treatment for esophageal cancer. We report a case of esophageal cancer with consciousness disorder due to hyperammonemia during FP treatment with an examination of some of the relevant literature. The patient was a man of approximately 70 years of age who was received FP treatment.
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- * He experienced severe symptoms, including headache and vomiting, 12 weeks post-surgery, leading to urgent hospitalization where tests revealed elevated CA19-9 levels and atypical cancer cells in his cerebrospinal fluid.
- * Diagnosed with meningeal carcinomatosis, he received a course of chemotherapy (CAPOX plus bevacizumab) but unfortunately died 18 weeks after the initial surgery.
Tumor-associated macrophages (TAMs) often assume an immunoregulatory M2 phenotype. Thus, the aim of the present study was to clarify the correlation of vascularity and TAMs, in particular the M2 phenotype in the stroma and tumor areas, with the clinical and pathological outcomes of patients with bladder cancer. The TAM counts and microvessel counts (MVCs) were determined immunohistochemically in 21 patients with bladder cancer.
View Article and Find Full Text PDFIntroduction: A hamartomatous polyp without associated mucocutaneous pigmentation or a family history of Peutz-Jeghers Syndrome is diagnosed as a solitary Peutz-Jeghers type hamartomatous polyp. As compared with Peutz-Jeghers Syndrome, Peutz-Jeghers type hamartomatous polyps are diagnosed with a lower risk of cancer and are regarded as a different disorder.
Case Presentation: In case one, we describe an 84-year-old Japanese man with a 14 mm duodenal polyp.