Publications by authors named "Akisa Tomita"

Article Synopsis
  • * Over 70% of the 1106 patients evaluated reported insomnia at their initial visit, with a small percentage (12.4%) continuing outpatient treatment for a year and showing significant improvement in insomnia.
  • * Findings indicate that addressing insomnia may be crucial for enhancing the treatment outcomes for patients with mental illnesses, as both insomnia and depressive symptoms were found to influence each other.
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Aim: Eye gaze measurement to human dialogue scenes in adults with attention deficit hyperactivity disorder (ADHD) was investigated. We examined whether eye gaze measurement might be a biological marker of ADHD.

Methods: Twenty-two individuals with ADHD (mean age, 34.

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Aim: Mind wandering (MW) has been closely associated with attention deficit hyperactivity disorder (ADHD); however, the field remains understudied in Japan. The present study examined MW in adults with ADHD using the Mind Excessively Wandering Scale (MEWS) in a Japanese clinical population.

Methods: Fifty-two adults with ADHD (mean age, 33.

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In this article, we review the downregulation of acetylcholinergic activity in schizophrenia and discuss the similarity and difference between Alzheimer's disease (AD) and schizophrenia in terms of acetylcholine (ACh) and anticholinergic activity (AA); then, we propose the use of cognition-enhancing therapy for schizophrenia. As ACh regulates an inflammatory system, when the cholinergic system is downregulated to a critical level, the inflammatory system is activated. We consider the possibility that AA appears endogenously in AD and accelerates AD pathology.

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We reported a procedure of serum anticholinergic activity (SAA) measurement and the reliability and reproducibility of the receptor binding assay, and we also described the usefulness of SAA measurement reflecting the anticholinergic activity (AA) in the central nervous system (CNS). According to the results of a 10 times repeated measurement of standard atropine binding, the relative error was between -5.5 and +3.

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